{"product_id":"proteintech-20703-1-ap","title":"Proteintech, 20703-1-AP, ABCB5 Polyclonal antibody","description":"Size: 20ul \/ 150ul\nThe ABCB5 (20703-1-AP) by Proteintech is a Polyclonal antibody targeting ABCB5 in WB, ELISA applications with reactivity to human samples\n20703-1-AP targets ABCB5 in WB, ELISA applications and shows reactivity with human samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: A431 cells, HT-29 cells,  Jurkat cells,  K-562 cells,  THP-1 cells\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:500-1:1000\n\u003cb\u003eBackground Information\u003c\/b\u003e\nABCB5 is an 812 amino acid multi-pass membrane protein and belongs to the ATP-binding cassette (ABC) transporter superfamily of integral membrane proteins (PMID: 15760339). ABCB5 is an Energy-dependent efflux transporter responsible for decreased drug accumulation in multidrug-resistant cells(PMID: 15899824, 15205344). ABCB5 acts as a marker of stem-like cells (CSC) in several malignancies and is responsible for the resistance to doxorubicin of a subset of malignant melanomas (PubMed:24934811, 15760339). Alternate splicing results in multiple transcript variants.\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human\nHost \/ Isotype: Rabbit \/ IgG\nClass: Polyclonal\nType: Antibody\nImmunogen: Peptide Predict reactive species\nFull Name: ATP-binding cassette, sub-family B (MDR\/TAP), member 5\nCalculated Molecular Weight: 90 kDa\nObserved Molecular Weight: 90-110 kDa\nGenBank Accession Number: NM_178559\nGene Symbol: ABCB5\nGene ID (NCBI): 340273\nRRID: AB_3085616\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Antigen affinity purification\nUNIPROT ID: Q2M3G0\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46869797732521,"sku":"20703-1-AP","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/proteintech-20703-1-ap","provider":"Iright","version":"1.0","type":"link"}