{"product_id":"proteintech-23601-1-ap","title":"Proteintech, 23601-1-AP, MSL2 Polyclonal antibody","description":"Size: 20ul \/ 150ul\nThe MSL2 (23601-1-AP) by Proteintech is a Polyclonal antibody targeting MSL2 in WB, ELISA applications with reactivity to human samples\n23601-1-AP targets MSL2 in WB, ELISA applications and shows reactivity with human samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: Jurkat cells, MOLT-4 cells\nPositive IF\/ICC detected in: A431 cells\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:1000-1:4000\nImmunofluorescence (IF)\/ICC: IF\/ICC : 1:200-1:800\n\u003cb\u003eBackground Information\u003c\/b\u003e\nIn mammals, MSL2 participates in histone H2B ubiquitination (H2Bub1) via the MSL complex, regulating transcription and chromatin remodeling.  It is essential for embryonic development and has been implicated in cancer progression.  MSL2's dysfunction is linked to developmental defects and oncogenesis, highlighting its critical role in gene regulation. (PMID: 30669413; PMID: 34899909)\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human\nHost \/ Isotype: Rabbit \/ IgG\nClass: Polyclonal\nType: Antibody\nImmunogen: CatNo: Ag18727 Product name: Recombinant human MSL2 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 228-577 aa of BC093790 Sequence: TEDLSDSLPPVCDTVATDLCSTGIDICSFSEDIKPGDSLLLSVEEVLRSLETVSNTEVCCPNLQPNLEATVSNGPFLQLSSQSLSHNVFMSTSPALHGLSCTAATPKIAKLNRKRSRSESDSEKVQPLPISTIIRGPTLGASAPVTVKRESKISLQPIATVPNGGTTPKISKTVLLSTKSMKKSHEHGSKKSHSKTKPGILKKDKAVKEKIPSHHFMPGSPTKTVYKKPQEKKGCKCGRATQNPSVLTCRGQRCPCYSNRKACLDCICRGCQNSYMANGEKKLEAFAVPEKALEQTRLTLGINVTSIAVRNASTSTSVINVTGSPVTTFLAASTHDDKSLDEAIDMRFDC Predict reactive species\nFull Name: male-specific lethal 2 homolog (Drosophila)\nCalculated Molecular Weight: 577 aa, 63 kDa\nObserved Molecular Weight: 70-75 kDa\nGenBank Accession Number: BC093790\nGene Symbol: MSL2\nGene ID (NCBI): 55167\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Antigen Affinity purified\nUNIPROT ID: Q9HCI7\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46887725826217,"sku":"23601-1-AP","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/proteintech-23601-1-ap","provider":"Iright","version":"1.0","type":"link"}