{"product_id":"proteintech-23712-1-ap","title":"Proteintech, 23712-1-AP, KCNK18 Polyclonal antibody","description":"Size: 20ul \/ 150ul\nThe KCNK18 (23712-1-AP) by Proteintech is a Polyclonal antibody targeting KCNK18 in WB, IF\/ICC, ELISA applications with reactivity to human samples\n23712-1-AP targets KCNK18 in WB, IF\/ICC, ELISA applications and shows reactivity with human samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: A431 cells,  A375 cells,  MCF-7 cells\nPositive IF\/ICC detected in: A375 cells\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:500-1:2000\nImmunofluorescence (IF)\/ICC: IF\/ICC : 1:50-1:500\n\u003cb\u003eBackground Information\u003c\/b\u003e\nKCNK18, also named as TRESK and TRIK, is an outward rectifying potassium channel which produces rapidly activating outward rectifier K+ currents. It may function as background potassium channel that sets the resting membrane potential. KCNK18 is inhibited by arachidonic acid and other naturally occurring unsaturated free fatty acids. KCNK18 channel activity is enhanced by volatile anesthetics, such as isoflurane. The gene of KCNK18 maps to chromosome 10q26.11, and encodes a 384-amino acid protein with a predicted unmodified molecular weight of 44 kDa. This antibody can be used to detect endogenous KCNK18, however, the reason for the additional band of 130-140 kDa is still unknown.\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human\nHost \/ Isotype: Rabbit \/ IgG\nClass: Polyclonal\nType: Antibody\nImmunogen: CatNo: Ag20514 Product name: Recombinant human KCNK18 protein Source: e coli. -derived, PET28a Tag: 6*His Domain: 143-290 aa of BC152979 Sequence: LMFLVLTDTGDILATILSTSYNRFRKFPFFTRPLLSKWCPKSLFKKKPDPKPADEAVPQIIISAEELPGPKLGTCPSRPSCSMELFERSHALEKQNTLQLPPQAMERSNSCPELVLGRLSYSIISNLDEVGQQVERLDIPLPIIALIV Predict reactive species\nFull Name: potassium channel, subfamily K, member 18\nCalculated Molecular Weight: 384 aa, 44 kDa\nObserved Molecular Weight: 44 kDa\nGenBank Accession Number: BC152979\nGene Symbol: KCNK18\nGene ID (NCBI): 338567\nRRID: AB_2879309\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Antigen affinity purification\nUNIPROT ID: Q7Z418\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46887691649193,"sku":"23712-1-AP","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/proteintech-23712-1-ap","provider":"Iright","version":"1.0","type":"link"}