{"product_id":"proteintech-23950-1-ap","title":"Proteintech, 23950-1-AP, MAP4K1 Polyclonal antibody","description":"Size: 20ul \/ 150ul\nThe MAP4K1 (23950-1-AP) by Proteintech is a Polyclonal antibody targeting MAP4K1 in WB, IHC, IP, ELISA applications with reactivity to human samples\n23950-1-AP targets MAP4K1 in WB, IHC, IF, IP, ELISA applications and shows reactivity with human samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: Daudi cells, Jurkat cells,  Raji cells,  Ramos cells\nPositive IP detected in: Jurkat cells\nPositive IHC detected in: human tonsillitis tissue, human liver tissueNote: suggested antigen retrieval withTE buffer pH 9.0;(*) Alternatively, antigen retrieval may be performed withcitrate buffer pH 6.0\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:2000-1:16000\nImmunoprecipitation (IP): IP : 0.5-4.0 ug for 1.0-3.0 mg of total protein lysate\nImmunohistochemistry (IHC): IHC : 1:50-1:500\n\u003cb\u003eBackground Information\u003c\/b\u003e\nMAP4K1(Mitogen-activated protein kinase kinase kinase kinase 1) is also named as MEKKK 1, HPK1 and belongs to the protein kinase superfamily. It may function as a novel tumor suppressor and its loss plays a critical role in pancreatic cancer. MAP4K1 regulates stress responses, proliferation, and apoptosis in hematopoietic cells. This protein has 2 isoforms produced by alternative splicing.\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human\nCited Reactivity: human, mouse\nHost \/ Isotype: Rabbit \/ IgG\nClass: Polyclonal\nType: Antibody\nImmunogen: CatNo: Ag20221 Product name: Recombinant human MAP4K1 protein Source: e coli. -derived, PET28a Tag: 6*His Domain: 364-551 aa of BC152994 Sequence: LRSSSPRKQLSESSDDDYDDVDIPTPAEDTPPPLPPKPKFRSPSDEGPGSMGDDGQLSPGVLVRCASGPPPNSPRPGPPPSTSSPHLTAHSEPSLWNPPSRELDKPPLLPPKKEKMKRKGCALLVKLFNGCPLRIHSTAAWTHPSTKDQHLLLGAEEGIFILNRNDQEATLEMLFPSRTTWVYSINNV Predict reactive species\nFull Name: mitogen-activated protein kinase kinase kinase kinase 1\nCalculated Molecular Weight: 833 aa, 91 kDa\nObserved Molecular Weight: 90 kDa\nGenBank Accession Number: BC152994\nGene Symbol: MAP4K1\nGene ID (NCBI): 11184\nRRID: AB_2879372\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Antigen Affinity purified\nUNIPROT ID: Q92918\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46869415297193,"sku":"23950-1-AP","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/proteintech-23950-1-ap","provider":"Iright","version":"1.0","type":"link"}