{"product_id":"proteintech-24226-1-ap","title":"Proteintech, 24226-1-AP, TMEM63B Polyclonal antibody","description":"Size: 20ul \/ 150ul\nThe TMEM63B (24226-1-AP) by Proteintech is a Polyclonal antibody targeting TMEM63B in WB, ELISA applications with reactivity to human, mouse samples\n24226-1-AP targets TMEM63B in WB, ELISA applications and shows reactivity with human, mouse samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: mouse kidney tissue\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:500-1:1000\n\u003cb\u003eBackground Information\u003c\/b\u003e\nTMEM63B, also known as C6orf110, belongs to the TMEM63 family. TMEM63B is a mechanosensitive cation channel activated by hypoosmotic stress and mechanic stimulation. Genetic deletion of TMEM63B is a cause of necroptosis of outer hair cells (OHCs) and progressive hearing loss (PMID: 32375046).\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human, mouse\nHost \/ Isotype: Rabbit \/ IgG\nClass: Polyclonal\nType: Antibody\nImmunogen: CatNo: Ag21573 Product name: Recombinant human TMEM63B protein Source: e coli. -derived, PET28a Tag: 6*His Domain: 700-832 aa of BC136769 Sequence: TMRTGFLAPTSMFTFVVLVITIVICLCHVCFGHFKYLSAHNYKIEHTETDTVDPRSNGRPPTAAAVPKSAKYIAQVLQDSEVDGDGDGAPGSSGDEPPSSSSQDEELLMPPDALTDTDFQSCEDSLIENEIHQ Predict reactive species\nFull Name: transmembrane protein 63B\nCalculated Molecular Weight: 832 aa, 95 kDa\nObserved Molecular Weight: 95 kDa\nGenBank Accession Number: BC136769\nGene Symbol: TMEM63B\nGene ID (NCBI): 55362\nRRID: AB_3085727\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Antigen Affinity purified\nUNIPROT ID: Q5T3F8\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46887833141417,"sku":"24226-1-AP","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/proteintech-24226-1-ap","provider":"Iright","version":"1.0","type":"link"}