{"product_id":"proteintech-24371-1-ap","title":"Proteintech, 24371-1-AP, TRIM61 Polyclonal antibody","description":"Size: 20ul \/ 150ul\nThe TRIM61 (24371-1-AP) by Proteintech is a Polyclonal antibody targeting TRIM61 in IHC, IF\/ICC, ELISA applications with reactivity to human, mouse samples\n24371-1-AP targets TRIM61 in IHC, IF\/ICC, ELISA applications and shows reactivity with human, mouse samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive IHC detected in: mouse liver tissueNote: suggested antigen retrieval withTE buffer pH 9.0;(*) Alternatively, antigen retrieval may be performed withcitrate buffer pH 6.0\nPositive IF\/ICC detected in: U2OS cells\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nImmunohistochemistry (IHC): IHC : 1:50-1:500\nImmunofluorescence (IF)\/ICC: IF\/ICC : 1:50-1:500\n\u003cb\u003eBackground Information\u003c\/b\u003e\nTRIM61 is a member of the tripartite motif (TRIM) protein family. The RING domain in TRIM proteins, including TRIM61, can mediate the conjugation of proteins with ubiquitin, small ubiquitin-like modifier (SUMO), or the ubiquitin-like molecule IFN-stimulated protein of 15 kDa (ISG15), contributing to the biological flexibility of TRIM proteins. The E3 ligase activity of TRIM proteins, such as TRIM61, is essential for their role in post-translational modification, which plays a crucial role in cellular processes often resulting in targeted degradation of conjugated proteins.\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human, mouse\nHost \/ Isotype: Rabbit \/ IgG\nClass: Polyclonal\nType: Antibody\nImmunogen: CatNo: Ag21656 Product name: Recombinant human TRIM61 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 176-209 aa of BC089393 Sequence: MESPSVTRLECSCTISAHFNLRLPGSSDSSASGS Predict reactive species\nFull Name: tripartite motif-containing 61\nCalculated Molecular Weight: 209 aa, 24 kDa\nGenBank Accession Number: BC089393\nGene Symbol: TRIM61\nGene ID (NCBI): 391712\nRRID: AB_3669434\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Antigen affinity purification\nUNIPROT ID: Q5EBN2\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46887838974121,"sku":"24371-1-AP","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/proteintech-24371-1-ap","provider":"Iright","version":"1.0","type":"link"}