{"product_id":"proteintech-24634-1-ap","title":"Proteintech, 24634-1-AP, TMPRSS11D Polyclonal antibody","description":"Size: 20ul \/ 150ul\nThe TMPRSS11D (24634-1-AP) by Proteintech is a Polyclonal antibody targeting TMPRSS11D in WB, ELISA applications with reactivity to human samples\n24634-1-AP targets TMPRSS11D in WB, ELISA applications and shows reactivity with human samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: A-253 cells\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:1000-1:4000\n\u003cb\u003eBackground Information\u003c\/b\u003e\nTMPRSS11D, also known as human airway trypsin-like protease (HAT), is a type II transmembrane serine protease that plays a crucial role in various biological processes, including viral infections and cancer progression. This protease is expressed in the epithelial cells of the respiratory tract and has been implicated in the activation of several viruses, such as SARS-CoV-2. In addition to its role in viral infections, TMPRSS11D has also been involved in cancer progression. High expression levels of TMPRSS11D have been associated with poor overall survival in non-small cell lung cancer. This suggests that TMPRSS11D may contribute to tumor growth and metastasis, making it a potential biomarker and therapeutic target in oncology. (PMID: 28086212, PMID: 40348740)\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human\nHost \/ Isotype: Rabbit \/ IgG\nClass: Polyclonal\nType: Antibody\nImmunogen: CatNo: Ag17841 Product name: Recombinant human TMPRSS11D protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 47-352 aa of BC125195 Sequence: SYFYRSSFQLLNVEYNSQLNSPATQEYRTLSGRIESLITKTFKESNLRNQFIRAHVAKLRQDGSGVRADVVMKFQFTRNNNGASMKSRIESVLRQMLNNSGNLEINPSTEITSLTDQAAANWLINECGAGPDLITLSEQRILGGTEAEEGSWPWQVSLRLNNAHHCGGSLINNMWILTAAHCFRSNSNPRDWIATSGISTTFPKLRMRVRNILIHNNYKSATHENDIALVRLENSVTFTKDIHSVCLPAATQNIPPGSTAYVTGWGAQEYAGHTVPELRQGQVRIISNDVCNAPHSYNGAILSGML Predict reactive species\nFull Name: transmembrane protease, serine 11D\nCalculated Molecular Weight: 418 aa, 46 kDa\nObserved Molecular Weight: 46 kDa\nGenBank Accession Number: BC125195\nGene Symbol: TMPRSS11D\nGene ID (NCBI): 9407\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Antigen affinity purification\nUNIPROT ID: O60235\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46887833829545,"sku":"24634-1-AP","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/proteintech-24634-1-ap","provider":"Iright","version":"1.0","type":"link"}