{"product_id":"proteintech-25613-1-ap","title":"Proteintech, 25613-1-AP, SMPD3 Polyclonal antibody","description":"Size: 20ul \/ 150ul\nThe SMPD3 (25613-1-AP) by Proteintech is a Polyclonal antibody targeting SMPD3 in WB, ELISA applications with reactivity to human samples\n25613-1-AP targets SMPD3 in WB, ELISA applications and shows reactivity with human samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: A549 cells, K-562 cells\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:500-1:2000\n\u003cb\u003eBackground Information\u003c\/b\u003e\nSMPD3 (sphingomyelin phosphodiesterase 3), also called neutral sphingomyelinase-2 (nSMase2), is a Golgi-enriched, membrane-bound Zn²⁺-dependent hydrolase that converts sphingomyelin into ceramide and phosphocholine.  Ceramide functions as a bioactive lipid second messenger that integrates cellular stress, apoptosis, autophagy and differentiation signals.\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human\nCited Reactivity: mouse\nHost \/ Isotype: Rabbit \/ IgG\nClass: Polyclonal\nType: Antibody\nImmunogen: CatNo: Ag22487 Product name: Recombinant human SMPD3 protein Source: e coli. -derived, PET30a Tag: 6*His Domain: 540-655 aa of BC112238 Sequence: PGEEKPWAIGTLLDTNGLYDEDVCTPDNLQKVLESEEGRREYLAFPTSKSSGQKGRKELLKGNGRRIDYMLHAEEGLCPDWKAEVEEFSFITQLSGLTDHLPVAMRLMVSSGEEEA Predict reactive species\nFull Name: sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II)\nCalculated Molecular Weight: 655 aa, 71 kDa\nObserved Molecular Weight: 70-71 kDa\nGenBank Accession Number: BC112238\nGene Symbol: SMPD3\nGene ID (NCBI): 55512\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Antigen affinity purification\nUNIPROT ID: Q9NY59\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46869768241321,"sku":"25613-1-AP","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/proteintech-25613-1-ap","provider":"Iright","version":"1.0","type":"link"}