{"product_id":"proteintech-25888-1-ap","title":"Proteintech, 25888-1-AP, AMHR2 Polyclonal antibody","description":"Size: 20ul \/ 150ul\nThe AMHR2 (25888-1-AP) by Proteintech is a Polyclonal antibody targeting AMHR2 in IHC, ELISA applications with reactivity to human, mouse samples\n25888-1-AP targets AMHR2 in IHC, ELISA applications and shows reactivity with human, mouse samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive IHC detected in: human testis tissue, human ovary tumor tissue,  mouse brain tissueNote: suggested antigen retrieval withTE buffer pH 9.0;(*) Alternatively, antigen retrieval may be performed withcitrate buffer pH 6.0\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nImmunohistochemistry (IHC): IHC : 1:50-1:500\n\u003cb\u003eBackground Information\u003c\/b\u003e\nAnti-Mullerian hormone (Amh) is the key factor in the regression of the  Mullerian ducts that is secreted by the Sertoli cells of the testis. As a member of the transforming growth factor β family, Amh signals through a heterodimeric receptor complex consisting of two type I and two types II serine\/threonine kinases receptors (J. Klatting, et. al, 2007). On ligand binding, Type II receptors phosphorylate and activate Type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. The Amh type II receptor (Amhr2) confers the specificity and is initially expressed in the coelomic epithelium next to the Mullerian ducts in both males and females (Zhan, y. et. al, 2006).\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human, mouse\nHost \/ Isotype: Rabbit \/ IgG\nClass: Polyclonal\nType: Antibody\nImmunogen: CatNo: Ag22473 Product name: Recombinant human AMHR2 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 225-573 aa of BC126316 Sequence: KLVAIKAFPPRSVAQFQAERALYELPGLQHDHIVRFITASRGGPGRLLSGPLLVLELHPKGSLCHYLTQYTSDWGSSLRMALSLAQGLAFLHEERWQNGQYKPGIAHRDLSSQNVLIREDGSCAIGDLGLALVLPGLTQPPAWTPTQPQGPAAIMEAGTQRYMAPELLDKTLDLQDWGMALRRADIYSLALLLWEILSRCPDLRPDSSPPPFQLAYEAELGNTPTSDELWALAVQERRRPYIPSTWRCFATDPDGLRELLEDCWDADPEARLTAECVQQRLAALAHPQESHPFPESCPRGCPPLCPEDCTSIPAPTILPCRPQRSACHFSVQQGPCSRNPQPACTLSPV Predict reactive species\nFull Name: anti-Mullerian hormone receptor, type II\nCalculated Molecular Weight: 573 aa, 63 kDa\nGenBank Accession Number: BC126316\nGene Symbol: AMHR2\nGene ID (NCBI): 269\nRRID: AB_3085826\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Antigen affinity purification\nUNIPROT ID: Q16671\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46869809004713,"sku":"25888-1-AP","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/proteintech-25888-1-ap","provider":"Iright","version":"1.0","type":"link"}