{"product_id":"proteintech-25892-1-ap","title":"Proteintech, 25892-1-AP, EDA Polyclonal antibody","description":"Size: 20ul \/ 150ul\nThe EDA (25892-1-AP) by Proteintech is a Polyclonal antibody targeting EDA in WB, IHC, ELISA applications with reactivity to human, mouse samples\n25892-1-AP targets EDA in WB, IHC, ELISA applications and shows reactivity with human, mouse samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: mouse liver tissue\nPositive IHC detected in: human liver tissueNote: suggested antigen retrieval withTE buffer pH 9.0;(*) Alternatively, antigen retrieval may be performed withcitrate buffer pH 6.0\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:200-1:1000\nImmunohistochemistry (IHC): IHC : 1:50-1:500\n\u003cb\u003eBackground Information\u003c\/b\u003e\nEDA (Ectodysplasin A) is a cytokine which is involved in epithelial-mesenchymal signaling during morphogenesis of ectodermal organs. It is a member of the tumor necrosis factor (TNF) superfamily, it orchestrates embryonic development of ectodermal structures including hair, teeth, nails, and sweat glands. EDA Functions as a ligand activating the DEATH-domain containing receptors EDAR and EDA2R, triggering NF-κB signaling cascades (PMID:11039935, 27144394, 34582123, 8696334).\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human, mouse\nCited Reactivity: human\nHost \/ Isotype: Rabbit \/ IgG\nClass: Polyclonal\nType: Antibody\nImmunogen: CatNo: Ag23154 Product name: Recombinant human EDA protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 1-132 aa of BC126143 Sequence: MGYPEVERRELLPAAAPRERGSQGCGCGGAPARAGEGNSCLLFLGFFGLSLALHLLTLCCYLELRSELRRERGAESRLGGSGTPGTSGTLSSLGGLDPDSPITSHLGQPSPKQQPLEPGEAALHSDSQDGHQ Predict reactive species\nFull Name: ectodysplasin A\nObserved Molecular Weight: 40 kDa\nGenBank Accession Number: BC126143\nGene Symbol: EDA\nGene ID (NCBI): 1896\nRRID: AB_2880286\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Antigen affinity purification\nUNIPROT ID: Q92838\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46869458190505,"sku":"25892-1-AP","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/proteintech-25892-1-ap","provider":"Iright","version":"1.0","type":"link"}