{"product_id":"proteintech-27422-1-ap","title":"Proteintech, 27422-1-AP, PRR11 Polyclonal antibody","description":"Size: 20ul \/ 150ul\nThe PRR11 (27422-1-AP) by Proteintech is a Polyclonal antibody targeting PRR11 in WB, ELISA applications with reactivity to human samples\n27422-1-AP targets PRR11 in WB, ELISA applications and shows reactivity with human samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: A549 cells, HeLa cells,  L02 cells,  MCF-7 cells\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:1000-1:5000\n\u003cb\u003eBackground Information\u003c\/b\u003e\nPRR11, or Proline-rich protein 11, is a protein-coding gene situated on chromosome 17q22-23, which plays a significant role in various cellular processes. The protein itself is composed of a nuclear localization signal (NLS), two proline-rich regions (PRs), and a zinc finger domain (ZFD) (PMID: 36551227). PRR11 has been implicated in the regulation of cell cycle, and it is involved in multiple aspects of cancer biology, including proliferation, migration, invasion, cell-cycle progression, apoptosis, autophagy, and chemotherapy resistance. It serves as a prognostic indicator in certain human cancers and is considered a potential target for therapeutic interventions (PMID: 36739300).\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human\nHost \/ Isotype: Rabbit \/ IgG\nClass: Polyclonal\nType: Antibody\nImmunogen: CatNo: Ag26636 Product name: Recombinant human PRR11 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 181-360 aa of BC008669 Sequence: ASHFPPPPPPPPLPPPPPPLAPVLLRKPSLAKALQAGPLKKDGPMQITVKDLLTVKLKKTQSLDEKRKLIPSPKARNPLVTVSDLQHVTLKPNSKVLSTRVTNVLITPGKSQMDLRKLLRKVDVERSPGGTPLTNKENMETGTGLTPVMTQALRRKFQLAHPRSPTPTLPLSTSSFDEQN Predict reactive species\nFull Name: proline rich 11\nCalculated Molecular Weight: 360 aa, 40 kDa\nObserved Molecular Weight: 38 kDa\nGenBank Accession Number: BC008669\nGene Symbol: PRR11\nGene ID (NCBI): 55771\nRRID: AB_3669600\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Antigen affinity purification\nUNIPROT ID: Q96HE9\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46887774978217,"sku":"27422-1-AP","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/proteintech-27422-1-ap","provider":"Iright","version":"1.0","type":"link"}