{"product_id":"proteintech-28092-1-ap","title":"Proteintech, 28092-1-AP, CACNA1H Polyclonal antibody","description":"Size: 20ul \/ 150ul\nThe CACNA1H (28092-1-AP) by Proteintech is a Polyclonal antibody targeting CACNA1H in WB, ELISA applications with reactivity to human samples\n28092-1-AP targets CACNA1H in WB, ELISA applications and shows reactivity with human samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: HeLa cells\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:500-1:2000\n\u003cb\u003eBackground Information\u003c\/b\u003e\nVoltage-dependent T-type calcium channel subunit alpha-1H (CACNA1H) is located in the plasma membrane of various tissues, including the brain cortex, amygdala, caudate nucleus, putamen, kidney, liver, and heart. This subunit regulates muscle contraction, secretion, neurotransmission, and gene expression by forming the pore (PMID: 33985586). Predominantly, the changes observed are missense mutations associated with gain-of-function, resulting in an increased influx of calcium into adrenal cells (PMID: 33985586; 37311830).\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human\nHost \/ Isotype: Rabbit \/ IgG\nClass: Polyclonal\nType: Antibody\nImmunogen: CatNo: Ag26094 Product name: Recombinant human CACNA1H protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 1181-1280 aa of NM_001005407 Sequence: MDGRAAPGPRATPLRRAESLDPRPLRPAALPPTKCRDRDGQVVALPSDFFLRIDSHREDAAELDDDSEDSCCLRLHKVLEPYKPQWCRSREAWALYLFSPQ Predict reactive species\nFull Name: calcium channel, voltage-dependent, T type, alpha 1H subunit\nCalculated Molecular Weight: 259 kDa\nObserved Molecular Weight: 259 kDa\nGenBank Accession Number: NM_001005407\nGene Symbol: CACNA1H\nGene ID (NCBI): 8912\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Antigen affinity purification\nUNIPROT ID: O95180\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46885727109289,"sku":"28092-1-AP","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/proteintech-28092-1-ap","provider":"Iright","version":"1.0","type":"link"}