{"product_id":"proteintech-28935-1-ap","title":"Proteintech, 28935-1-AP, Phospho-MEK1 (Thr386) Polyclonal antibody","description":"Size: 20ul \/ 100ul\nThe Phospho-MEK1 (Thr386) (28935-1-AP) by Proteintech is a Polyclonal antibody targeting Phospho-MEK1 (Thr386) in WB, IF\/ICC, ELISA applications with reactivity to human samples\n28935-1-AP targets Phospho-MEK1 (Thr386) in WB, IF\/ICC, ELISA applications and shows reactivity with human samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: λ phosphatase treated HeLa cells\nPositive IF\/ICC detected in: λ phosphatase treated HeLa cells\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:1000-1:4000\nImmunofluorescence (IF)\/ICC: IF\/ICC : 1:50-1:500\n\u003cb\u003eBackground Information\u003c\/b\u003e\nMEK1 is also named as MAP2K1 (mitogen-activated protein kinase kinase 1), MAPKK1, PRKMK1, MKK1 and belongs to the MAP kinase kinase subfamily. It is a dual-specificity kinase that mediate ERK1 and ERK2 activation during adhesion and growth factor signaling(PMID:19219045). It also plays an essential role in extra-embryonic ectoderm during placentogenesis. MEK1 has 2 isoforms produced by alternative splicing with the molecular weight of 43 kDa and 41 kDa. MEK1 may form a  heterodimer with MEK2.(PMID:21144847,19219045).\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human\nHost \/ Isotype: Rabbit \/ IgG\nClass: Polyclonal\nType: Antibody\nImmunogen: Peptide Predict reactive species\nFull Name: mitogen-activated protein kinase kinase 1\nCalculated Molecular Weight: 43 kDa\nObserved Molecular Weight: 40-45 kDa\nGenBank Accession Number: BC139729\nGene Symbol: MEK1\nGene ID (NCBI): 5604\nENSEMBL Gene ID: ENSG00000169032\nRRID: AB_2918218\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Antigen affinity purification\nUNIPROT ID: Q02750\nStorage Buffer: PBS with 0.02% sodium azide, 50% glycerol, and 0.05% BSA, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46887760461993,"sku":"28935-1-AP","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/proteintech-28935-1-ap","provider":"Iright","version":"1.0","type":"link"}