{"product_id":"proteintech-28945-1-ap","title":"Proteintech, 28945-1-AP, Phospho-STAT3 (Ser727) Polyclonal antibody","description":"Size: 20ul \/ 100ul\nThe Phospho-STAT3 (Ser727) (28945-1-AP) by Proteintech is a Polyclonal antibody targeting Phospho-STAT3 (Ser727) in WB, ELISA applications with reactivity to human samples\n28945-1-AP targets Phospho-STAT3 (Ser727) in WB, IF, ELISA applications and shows reactivity with human samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: HEK-293T cells, λ phosphatase treated HEK-293T cells\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:1000-1:4000\n\u003cb\u003eBackground Information\u003c\/b\u003e\nSignal transducer and activator of transcription 3 (acute-phase response factor) (STAT3, synonyms: APRF, FLJ20882, MGC16063) is a member of the STAT protein family. Phosphorylated STAT3 dimerizes and translocates to the nucleus, where it regulates the transcription of target genes through binding to specific DNA-responsive elements. In addition to activation by Tyr705 phosphorylation, STAT3 also requires phosphorylation on Ser727 to achieve maximal transcriptional activity. (PMID: 21617181)\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human\nCited Reactivity: human, mouse, rat, bovine\nHost \/ Isotype: Rabbit \/ IgG\nClass: Polyclonal\nType: Antibody\nImmunogen: Peptide Predict reactive species\nFull Name: signal transducer and activator of transcription 3 (acute-phase response factor)\nCalculated Molecular Weight: 770 aa, 88 kDa\nObserved Molecular Weight: 92-100 kDa\nGenBank Accession Number: BC000627\nGene Symbol: STAT3\nGene ID (NCBI): 6774\nRRID: AB_3206262\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Antigen affinity purification\nUNIPROT ID: P40763\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46868864991401,"sku":"28945-1-AP","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/proteintech-28945-1-ap","provider":"Iright","version":"1.0","type":"link"}