{"product_id":"proteintech-29027-1-ap","title":"Proteintech, 29027-1-AP, Phospho-MOBKL1B (Thr12) Polyclonal antibody","description":"Size: 20ul \/ 100ul\nThe Phospho-MOBKL1B (Thr12) (29027-1-AP) by Proteintech is a Polyclonal antibody targeting Phospho-MOBKL1B (Thr12) in WB, IF\/ICC, ELISA applications with reactivity to human, rat samples\n29027-1-AP targets Phospho-MOBKL1B (Thr12) in WB, IF\/ICC, ELISA applications and shows reactivity with human, rat samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: PC-12 cells, λ phosphatase treated PC-12 cells\nPositive IF\/ICC detected in: λ phosphatase treated U2OS cells\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:500-1:1000\nImmunofluorescence (IF)\/ICC: IF\/ICC : 1:50-1:500\n\u003cb\u003eBackground Information\u003c\/b\u003e\nMOBKL1B, also known as MOB1B, belongs to the MOB1\/phocein family. MOBKL1B binds to and regulate downstream targets such as the NDR-family protein kinases and LATS1 kinase. MOB1 protein is a key regulator of large tumor suppressor 1\/2 (LATS1\/2) kinases in the Hippo pathway. MOBKL1A and MOBKL1B are phosphorylated by MST1\/MST2 kinases at Thr35 and Thr12, and MST1\/MST2-catalyzed phosphorylation of MOBKL1A\/MOBKL1B in intact cells is sufficient to substantially retard cell-cycle progression (PMID: 18328708).\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human, rat\nCited Reactivity: human, mouse\nHost \/ Isotype: Rabbit \/ IgG\nClass: Polyclonal\nType: Antibody\nImmunogen: Peptide Predict reactive species\nFull Name: MOB1, Mps One Binder kinase activator-like 1B (yeast)\nCalculated Molecular Weight: 216 aa, 25 kDa\nObserved Molecular Weight: 25 kDa\nGenBank Accession Number: BC003398\nGene Symbol: MOBKL1B\nGene ID (NCBI): 55233\nRRID: AB_2923589\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Antigen affinity purification\nUNIPROT ID: Q9H8S9\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46869729149097,"sku":"29027-1-AP","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/proteintech-29027-1-ap","provider":"Iright","version":"1.0","type":"link"}