{"product_id":"proteintech-29117-1-ap","title":"Proteintech, 29117-1-AP, Phospho-RICTOR (Thr1135) Polyclonal antibody","description":"Size: 20ul \/ 100ul\nThe Phospho-RICTOR (Thr1135) (29117-1-AP) by Proteintech is a Polyclonal antibody targeting Phospho-RICTOR (Thr1135) in WB, ELISA applications with reactivity to Human samples\n29117-1-AP targets Phospho-RICTOR (Thr1135) in WB, ELISA applications and shows reactivity with Human samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: PDGF treated PC-3 cells\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:500-1:2000\n\u003cb\u003eBackground Information\u003c\/b\u003e\nRictor is the core component of the mammalian target of rapamycin complex 2 (mTORC2), and loss of this protein leads to an immunodeficiency. RICTOR is regulated by phosphorylation at threonine 1135 (Thr1135) by S6K, downstream of PI3K, which inactivates mTORC2 and therefore inhibits AKT phosphorylation at Ser473. (PMID: 26356562, PMID: 28821013)\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: Human\nHost \/ Isotype: Rabbit \/ IgG\nClass: Polyclonal\nType: Antibody\nImmunogen: Peptide Predict reactive species\nFull Name: rapamycin-insensitive companion of mTOR\nCalculated Molecular Weight: 192 kDa\nObserved Molecular Weight: 192-200 kDa\nGenBank Accession Number: BC029608\nGene Symbol: RICTOR\nGene ID (NCBI): 253260\nRRID: AB_3085343\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Antigen affinity purification\nUNIPROT ID: Q6R327\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46887761215657,"sku":"29117-1-AP","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/proteintech-29117-1-ap","provider":"Iright","version":"1.0","type":"link"}