{"product_id":"proteintech-29199-1-ap","title":"Proteintech, 29199-1-AP, Phospho-MKK7 (Ser271\/Thr275) Polyclonal antibody","description":"Size: 20ul \/ 100ul\nThe Phospho-MKK7 (Ser271\/Thr275) (29199-1-AP) by Proteintech is a Polyclonal antibody targeting Phospho-MKK7 (Ser271\/Thr275) in WB, ELISA applications with reactivity to Human samples\n29199-1-AP targets Phospho-MKK7 (Ser271\/Thr275) in WB, ELISA applications and shows reactivity with Human samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: Calyculin A treated HEK-293 cells\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:2000-1:16000\n\u003cb\u003eBackground Information\u003c\/b\u003e\nDual specificity mitogen-activated protein kinase kinase 7 (MKK7), also known as MEK7 or MAP2K7, is a member of mitogen-activated kinase kinase (MAP2K) subfamily, and a key activator of c-Jun N-terminal kinase (JNK) signaling, a pathway that regulates primarily stress and inflammatory responses. MKK7 activity can be increased by either MKK7-autophosphorylation or phosphorylation of the Ser and Thr residues of the S-X-A-K-T motifs in the Kinase domain by upstream MEKK1, MEKK2, or MLK3.(PMID: 32783966, PMID: 31579105)\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: Human\nHost \/ Isotype: Rabbit \/ IgG\nClass: Polyclonal\nType: Antibody\nImmunogen: Peptide Predict reactive species\nFull Name: mitogen-activated protein kinase kinase 7\nCalculated Molecular Weight: 47 kDa\nObserved Molecular Weight: 47-52 kDa\nGenBank Accession Number: BC038295\nGene Symbol: MKK7\nGene ID (NCBI): 5609\nRRID: AB_2918246\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Antigen affinity purification\nUNIPROT ID: O14733\nStorage Buffer: PBS with 0.02% sodium azide, 50% glycerol, and 0.05% BSA, pH 7.3.\nStorage Conditions: Store at -20°C. Aliquoting is unnecessary for -20 o C storage.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46887760593065,"sku":"29199-1-AP","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/proteintech-29199-1-ap","provider":"Iright","version":"1.0","type":"link"}