{"product_id":"proteintech-29208-1-ap","title":"Proteintech, 29208-1-AP, PKC Gamma Polyclonal antibody","description":"Size: 20ul \/ 150ul\nThe PKC Gamma (29208-1-AP) by Proteintech is a Polyclonal antibody targeting PKC Gamma in WB, IHC, ELISA applications with reactivity to Human, mouse, rat samples\n29208-1-AP targets PKC Gamma in WB, IHC, IF, ELISA applications and shows reactivity with Human, mouse, rat samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: mouse brain tissue, rat brain tissue\nPositive IHC detected in: mouse cerebellum tissueNote: suggested antigen retrieval withTE buffer pH 9.0;(*) Alternatively, antigen retrieval may be performed withcitrate buffer pH 6.0\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:1000-1:4000\nImmunohistochemistry (IHC): IHC : 1:50-1:500\n\u003cb\u003eBackground Information\u003c\/b\u003e\nProtein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC gamma is a neuron-specific member of the classical PKCs and is activated and translocated to subcellular regions as a result of various stimuli, including diacylglycerol synthesis, increased intracellular Ca(2+) and phorbol esters. Defects in this protein have been associated with spinocerebellar ataxia type 14 (SCA14), an autosomal dominant neurodegenerative disease.\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: Human, mouse, rat\nCited Reactivity: human, mouse\nHost \/ Isotype: Rabbit \/ IgG\nClass: Polyclonal\nType: Antibody\nImmunogen: CatNo: Ag25085 Product name: Recombinant human PRKCG protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 600-641 aa of BC047876 Sequence: SGPDGEPTIRAHGFFRWIDWERLERLEIPPPFRPRPCGRSGE Predict reactive species\nFull Name: protein kinase C, gamma\nCalculated Molecular Weight: 78 kDa\nObserved Molecular Weight: 78 kDa\nGenBank Accession Number: BC047876\nGene Symbol: PKC Gamma\nGene ID (NCBI): 5582\nRRID: AB_2918249\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Antigen affinity purification\nUNIPROT ID: P05129\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46869572812969,"sku":"29208-1-AP","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/proteintech-29208-1-ap","provider":"Iright","version":"1.0","type":"link"}