{"product_id":"proteintech-29574-1-ap","title":"Proteintech, 29574-1-AP, Phospho-INPPL1 (Tyr986\/987) Polyclonal antibody","description":"Size: 20ul \/ 100ul\nThe Phospho-INPPL1 (Tyr986\/987) (29574-1-AP) by Proteintech is a Polyclonal antibody targeting Phospho-INPPL1 (Tyr986\/987) in WB, ELISA applications with reactivity to Human, mouse samples\n29574-1-AP targets Phospho-INPPL1 (Tyr986\/987) in WB, ELISA applications and shows reactivity with Human, mouse samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: UV treated HeLa cells, UV treated NIH\/3T3 cells,  HeLa cells\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:500-1:1000\n\u003cb\u003eBackground Information\u003c\/b\u003e\nInositol polyphosphate phosphatase-like protein 1(INPPL1) belongs to the inositol and phosphatidylinositol 5-phosphatase family, also known as SH2 domain-containing inositol 5'-phosphatase 2(SHIP2), is ubiquitous in all organizations. SHIP2 is constitutively tyrosine-phosphorylated in chronic myeloid leukemia progenitor cells. In B cells, SHIP2 was most tyrosine phosphorylated after BCR and FC-γriib crosslinking and was associated with Shc, but not after BCR stimulation alone. It has also been shown that SHIP2 can be phosphorylated at Tyr-986 in COS-7 cells and Chinese hamster ovary cells overexpressing the insulin receptor. (PMID: 11349134)\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: Human, mouse\nHost \/ Isotype: Rabbit \/ IgG\nClass: Polyclonal\nType: Antibody\nImmunogen: Peptide Predict reactive species\nFull Name: inositol polyphosphate phosphatase-like 1\nCalculated Molecular Weight: 1258 aa, 139 kDa\nObserved Molecular Weight: 150 kDa\nGenBank Accession Number: BC140853\nGene Symbol: INPPL1\nGene ID (NCBI): 3636\nRRID: AB_3085347\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Antigen affinity purification\nUNIPROT ID: O15357\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46887760003241,"sku":"29574-1-AP","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/proteintech-29574-1-ap","provider":"Iright","version":"1.0","type":"link"}