{"product_id":"proteintech-29580-1-ap","title":"Proteintech, 29580-1-AP, Phospho-PDH E1 Alpha (Ser293) Polyclonal antibody","description":"Size: 20ul \/ 100ul\nThe Phospho-PDH E1 Alpha (Ser293) (29580-1-AP) by Proteintech is a Polyclonal antibody targeting Phospho-PDH E1 Alpha (Ser293) in WB, ELISA applications with reactivity to human samples\n29580-1-AP targets Phospho-PDH E1 Alpha (Ser293) in WB, ELISA applications and shows reactivity with human samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: HeLa cells, λ phosphatase treated HeLa cells\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:500-1:2000\n\u003cb\u003eBackground Information\u003c\/b\u003e\nPDHA1(Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial) is also named as PHE1A. Multiple post-translational modifications (PTMs) of PDHA1 have been identified, such as acetylation, succinylation, and tyrosine phosphorylation. However, most of these PTMs ultimately affect PDHA1 activity through their influence on the phosphorylation of Ser293, Ser232, and Ser300 which are regulated by PDKs(pyruvate dehydrogenase kinases) and PDPs(pyruvate dehydrogenase phosphatases).(PMID: 34667275)\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human\nHost \/ Isotype: Rabbit \/ IgG\nClass: Polyclonal\nType: Antibody\nImmunogen: Peptide Predict reactive species\nFull Name: pyruvate dehydrogenase (lipoamide) alpha 1\nCalculated Molecular Weight: 43 kDa\nObserved Molecular Weight: 40 kDa\nGenBank Accession Number: BC002406\nGene Symbol: PDHA1\nGene ID (NCBI): 5160\nRRID: AB_3669690\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Antigen affinity purification\nUNIPROT ID: P08559\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46887760789673,"sku":"29580-1-AP","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/proteintech-29580-1-ap","provider":"Iright","version":"1.0","type":"link"}