{"product_id":"proteintech-29934-1-ap","title":"Proteintech, 29934-1-AP, GPR179 Polyclonal antibody","description":"Size: 20ul \/ 150ul\nThe GPR179 (29934-1-AP) by Proteintech is a Polyclonal antibody targeting GPR179 in WB, IHC, ELISA applications with reactivity to human, mouse samples\n29934-1-AP targets GPR179 in WB, IHC, ELISA applications and shows reactivity with human, mouse samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: HeLa cells\nPositive IHC detected in: mouse liver tissueNote: suggested antigen retrieval withTE buffer pH 9.0;(*) Alternatively, antigen retrieval may be performed withcitrate buffer pH 6.0\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:1000-1:6000\nImmunohistochemistry (IHC): IHC : 1:250-1:1000\n\u003cb\u003eBackground Information\u003c\/b\u003e\nGPR179 (Probable G-protein coupled receptor 179) belongs to the glutamate receptor subfamily of GPCRs, which is involved in signal transduction through retinal depolarizing bipolar cells. The protein has an EGF-like calcium binding domain and a seven transmembrane domain in the N-terminal region of the protein. Mutations in this gene are associated with congenital stationary night blindness type 1E. GPR179 is expressed in retinal bipolar cells and upregulated in rd1 mice retina with Pde6b mutations (PubMed: 22325361, PubMed: 22325362).\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human, mouse\nHost \/ Isotype: Rabbit \/ IgG\nClass: Polyclonal\nType: Antibody\nImmunogen: CatNo: Ag32180 Product name: Recombinant human GPR179 protein Source: e coli. -derived, PET28a Tag: 6*His Domain: 26-381 aa of NM_001004334.3 Sequence: LGGPRPIRSLPPLSSQVKPGSVPMQVPLEGAEAALAYLYSGDAQQLSQVNCSERYEARGAGAMPGLPPSLQGAAGTLAQAANFLNMLLQANDIRESSVEEDVEWYQALVRSVAEGDPRVYRALLTFNPPPGASHLQLALQATRTGEETILQDLSGNWVQEENPPGDLDTPALKKRVLTNDLGSLGSPKWPQADGYVGDTQQVRLSPPFLECQEGRLRPGWLITLSATFYGLKPDLSPEVRGQVQMDVDLQSVDINQCASGPGWYSNTHLCDLNSTQCVPLESQGFVLGRYLCRCRPGFYGASPSGGLEESDFQTTGQFGFPEGRSGRLLQCLPCPEGCTSCMDATPCLVEEAAVLR Predict reactive species\nFull Name: G protein-coupled receptor 179\nCalculated Molecular Weight: 257 kDa\nObserved Molecular Weight: 260-270 kDa\nGenBank Accession Number: NM_001004334.3\nGene Symbol: GPR179\nGene ID (NCBI): 440435\nRRID: AB_2923622\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Antigen affinity purification\nUNIPROT ID: Q6PRD1\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46887657242793,"sku":"29934-1-AP","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/proteintech-29934-1-ap","provider":"Iright","version":"1.0","type":"link"}