{"product_id":"proteintech-30263-1-ap","title":"Proteintech, 30263-1-AP, Phospho-EPHA2 (Tyr588) Polyclonal antibody","description":"Size: 20ul \/ 100ul\nThe Phospho-EPHA2 (Tyr588) (30263-1-AP) by Proteintech is a Polyclonal antibody targeting Phospho-EPHA2 (Tyr588) in WB, ELISA applications with reactivity to Human samples\n30263-1-AP targets Phospho-EPHA2 (Tyr588) in WB, ELISA applications and shows reactivity with Human samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: MG132 treated HepG2 cells\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:500-1:2000\n\u003cb\u003eBackground Information\u003c\/b\u003e\nEphrin type-A receptor 2 (EPHA2), belongs to the receptor tyrosine kinases (RTKs) family, that binds promiscuously membrane-bound ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. Research studies have shown that Eph receptors and ligands may be involved in many diseases including cancer (PMID: 11114742). The \"reverse signaling\" function, whereby the cytoplasmic domain becomes tyrosine phosphorylated, allows interactions with other proteins that may activate signaling pathways in the ligand-expressing cells. The detected molecular weight is around 110 kDa.\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: Human\nCited Reactivity: human\nHost \/ Isotype: Rabbit \/ IgG\nClass: Polyclonal\nType: Antibody\nImmunogen: Peptide Predict reactive species\nFull Name: EPH receptor A2\nCalculated Molecular Weight: 976 aa, 108 kDa\nObserved Molecular Weight: 110 kDa\nGenBank Accession Number: BC037166\nGene Symbol: EPHA2\nGene ID (NCBI): 1969\nRRID: AB_2935423\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Antigen affinity purification\nUNIPROT ID: P29317\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46869728788649,"sku":"30263-1-AP","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/proteintech-30263-1-ap","provider":"Iright","version":"1.0","type":"link"}