{"product_id":"proteintech-30354-1-ap","title":"Proteintech, 30354-1-AP, GSDMA Polyclonal antibody","description":"Size: 20ul \/ 150ul\nThe GSDMA (30354-1-AP) by Proteintech is a Polyclonal antibody targeting GSDMA in WB, ELISA applications with reactivity to Human, mouse samples\n30354-1-AP targets GSDMA in WB, ELISA applications and shows reactivity with Human, mouse samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: COLO 320 cells, Daudi cells,  mouse stomach tissue,  mouse skin tissue\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:2000-1:14000\n\u003cb\u003eBackground Information\u003c\/b\u003e\nGasdermins, a family of five pore-forming proteins (GSDMA-GSDME) in humans expressed predominantly in the skin, mucosa and immune sentinel cells, are key executioners of inflammatory cell death (pyroptosis), which recruits immune cells to infection sites and promotes protective immunity. GSDMA was predicted to enable phosphatidylinositol-4,5-bisphosphate binding activity, phosphatidylinositol-4-phosphate binding activity, and phosphatidylserine binding activity. Involved in apoptotic process.\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: Human, mouse\nHost \/ Isotype: Rabbit \/ IgG\nClass: Polyclonal\nType: Antibody\nImmunogen: CatNo: Ag31284 Product name: Recombinant human GSDMA protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 232-445 aa of BC109197 Sequence: PPGEKSGEEKVILIQASDVGDVHEGFRTLKEEVQRETQQVEKLSRVGQSSLLSSLSKLLGKKKELQDLELALEGALDKGHEVNLEALPKDVLLSKEAVGAILYFVGALTELSEAQQKLLVKSMEKKILPVQLKLVESTMEQNFLLDKEGVFPLQPELLSSLGDEELTLTEALVGLSGLEVQRSGPQYMWDPDTLPRLCALYAGLSLLQQLTKAS Predict reactive species\nFull Name: gasdermin A\nCalculated Molecular Weight: 445 aa, 49 kDa\nObserved Molecular Weight: 49 kDa\nGenBank Accession Number: BC109197\nGene Symbol: GSDMA\nGene ID (NCBI): 284110\nRRID: AB_3086299\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Antigen affinity purification\nUNIPROT ID: Q96QA5\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46887660585129,"sku":"30354-1-AP","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/proteintech-30354-1-ap","provider":"Iright","version":"1.0","type":"link"}