{"product_id":"proteintech-30356-1-ap","title":"Proteintech, 30356-1-AP, FCGR3A\/CD16a Polyclonal antibody","description":"Size: 20ul \/ 150ul\nThe FCGR3A\/CD16a (30356-1-AP) by Proteintech is a Polyclonal antibody targeting FCGR3A\/CD16a in WB, IF-P, ELISA applications with reactivity to human samples\n30356-1-AP targets FCGR3A\/CD16a in WB, IHC, IF-P, ELISA applications and shows reactivity with human samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: HL-60 cells, Jurkat cells\nPositive IF-P detected in: mouse spleen tissue\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:500-1:3000\nImmunofluorescence (IF)-P: IF-P : 1:50-1:500\n\u003cb\u003eBackground Information\u003c\/b\u003e\nCD16 is a  low affinity Fc receptor. It has been identified as Fc receptors FcγRIIIa (CD16a) and FcγRIIIb (CD16b), encoded by two nearly identical genes, FCGR3A and the FCGR3B.  In humans, FcγRIIIa\/CD16a is a type I transmembrane receptor expressed on macrophages and NK cells. FcγRIIIb\/CD16b is a GPI-linked Fc-receptor highly expressed on neutrophils. The two proteins differ by only four amino acid residues  in the mature proteins(PMID: 30361439). FCGR3A has a calculated molecular weight of 29 kDa, with an apparent molecular weight of 50-80 kDa due to extensive glycosylation (PMID: 30655272; PMID: 27914599). The antibody is specific for FCGR3A\/CD16a.\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human\nCited Reactivity: human\nHost \/ Isotype: Rabbit \/ IgG\nClass: Polyclonal\nType: Antibody\nImmunogen: CatNo: Ag1281 Product name: Recombinant human FCGR3A protein Source: e coli. -derived, Unknow Tag: N\/A Domain: 80cn of BC036723 Sequence: Predict reactive species\nFull Name: Fc fragment of IgG, low affinity IIIa, receptor (CD16a)\nCalculated Molecular Weight: 29 kDa\nObserved Molecular Weight: 65-70 kDa\nGenBank Accession Number: BC036723\nGene Symbol: CD16a\nGene ID (NCBI): 2214\nENSEMBL Gene ID: ENSG00000203747\nRRID: AB_3086300\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Antigen affinity purification\nUNIPROT ID: P08637\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46869682978985,"sku":"30356-1-AP","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/proteintech-30356-1-ap","provider":"Iright","version":"1.0","type":"link"}