{"product_id":"proteintech-30455-1-ap","title":"Proteintech, 30455-1-AP, NLRC3 Polyclonal antibody","description":"Size: 20ul \/ 150ul\nThe NLRC3 (30455-1-AP) by Proteintech is a Polyclonal antibody targeting NLRC3 in WB, ELISA applications with reactivity to Human samples\n30455-1-AP targets NLRC3 in WB, ELISA applications and shows reactivity with Human samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: Daudi cells, Jurkat cells,  Raji cells,  Ramos cells\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:1000-1:4000\n\u003cb\u003eBackground Information\u003c\/b\u003e\nNLRC3 is a member of the pattern recognition receptors nucleotide-binding oligomerization domain (NOD)-like receptors (NLRs) family, and plays a pivotal regulatory role in modulating the activation of immune cells. In macrophages, NLRC3 inhibits the activation of the NF-κB signaling pathway, the STING\/TBK1 signaling pathway, and the formation of the inflammasome. In the context of T cells immune response, NLRC3 prevents the activation of T cells by regulating the function of dendritic cells and directly influencing the function of T cells.\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: Human\nHost \/ Isotype: Rabbit \/ IgG\nClass: Polyclonal\nType: Antibody\nImmunogen: CatNo: Ag32323 Product name: Recombinant human NLRC3 protein Source: e coli. -derived, PET28a Tag: 6*His Domain: 1-130 aa of NM_178844 Sequence: MRKQEVRTGREAGQGHGTGSPAEQVKALMDLLAGKGSQGSQAPQALDRTPDAPLGPCSNDSRIQRHRKALLSKVGGGPELGGPWHRLASLLLVEGLTDLQLREHDFTQVEATRGGGHPARTVALDRLFLP Predict reactive species\nFull Name: NLR family, CARD domain containing 3\nCalculated Molecular Weight: 115 kDa\nObserved Molecular Weight: 100-110 kDa\nGenBank Accession Number: NM_178844\nGene Symbol: NLRC3\nGene ID (NCBI): 197358\nRRID: AB_3086322\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Antigen affinity purification\nUNIPROT ID: Q7RTR2\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46887738671273,"sku":"30455-1-AP","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/proteintech-30455-1-ap","provider":"Iright","version":"1.0","type":"link"}