{"product_id":"proteintech-31597-1-ap","title":"Proteintech, 31597-1-AP, Phospho-SAMHD1 (Thr592) Polyclonal antibody","description":"Size: 20ul \/ 100ul\nThe Phospho-SAMHD1 (Thr592) (31597-1-AP) by Proteintech is a Polyclonal antibody targeting Phospho-SAMHD1 (Thr592) in WB, ELISA applications with reactivity to human samples\n31597-1-AP targets Phospho-SAMHD1 (Thr592) in WB, ELISA applications and shows reactivity with human samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: THP-1 cells, λ phosphatase treated THP-1 cells\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:500-1:2000\n\u003cb\u003eBackground Information\u003c\/b\u003e\nSAMHD1 is a GTP\/dGTP-activated deoxynucleotide triphosphohydrolase. Human SAMHD1 is a 626 amino acid protein comprising an N-terminal nuclear localisation signal, two major structural domains. SAMHD1 has been reported to have alternative nuclease and\/or RNA binding activities that, dependent on the cellular circumstances, can also mediate restriction of HIV-1. In addition, restriction is regulated by Threonine 592 phosphorylation and removing this regulation may enable SAMHD1 to inhibit HIV-1 in cycling cells.\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human\nHost \/ Isotype: Rabbit \/ IgG\nClass: Polyclonal\nType: Antibody\nImmunogen: Peptide Predict reactive species\nFull Name: SAM domain and HD domain 1\nCalculated Molecular Weight: 626 aa, 72 kDa\nObserved Molecular Weight: 72 kDa\nGenBank Accession Number: BC036450\nGene Symbol: SAMHD1\nGene ID (NCBI): 25939\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Antigen affinity purification\nUNIPROT ID: Q9Y3Z3\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46887761248425,"sku":"31597-1-AP","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/proteintech-31597-1-ap","provider":"Iright","version":"1.0","type":"link"}