{"product_id":"proteintech-31841-1-ap","title":"Proteintech, 31841-1-AP, FAAP100 Polyclonal antibody","description":"Size: 20ul \/ 150ul\nThe FAAP100 (31841-1-AP) by Proteintech is a Polyclonal antibody targeting FAAP100 in WB, ELISA applications with reactivity to human samples\n31841-1-AP targets FAAP100 in WB, ELISA applications and shows reactivity with human samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: A431 cells, HL-60 cells,  Jurkat cells,  SH-SY5Y cells\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:500-1:3000\n\u003cb\u003eBackground Information\u003c\/b\u003e\nFA core complex associated protein 100 (FAAP100, also known as C17orf70) is a component of the Fanconi anemia (FA), which plays a role in the FA-associated DNA damage response network as well as regulates Fanconi anemia group D2 protein (FANCD2) monoubiquitination and the stability of the FA core complex (PMID: 17396147). FAAP100 deletion leads to FA pathway inactivation, increases TRCs and cotranscriptional R-loops, and contributes to the collapse of replication forks and the generation of DNA damage (PMID: 37580696).\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human\nHost \/ Isotype: Rabbit \/ IgG\nClass: Polyclonal\nType: Antibody\nImmunogen: CatNo: Ag36385 Product name: Recombinant human C17orf70 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 524-730 aa of BC117139 Sequence: PVATFLETCREPGSQPAGPASLRAEYLPPSVASIKVSAELLRAALKDGHSGVPLCCATLQWLLAENAAVDVVRARALSSIQGVAPDGANVHLIVREVAMTDLCPAGPIQAVEIQVESSSLADICRAHHAVVGRMQTMVTEQAAQGSSAPDLRVQYLRQIHANHETLLREVQTLRDRLCTEDEASSCATAQRLLQVYRQLRHPSLILL Predict reactive species\nFull Name: chromosome 17 open reading frame 70\nCalculated Molecular Weight: 93 kDa\nObserved Molecular Weight: 100 kDa\nGenBank Accession Number: BC117139\nGene Symbol: C17orf70\nGene ID (NCBI): 80233\nRRID: AB_3670125\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Antigen affinity Purification\nUNIPROT ID: Q0VG06\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46887629160617,"sku":"31841-1-AP","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/proteintech-31841-1-ap","provider":"Iright","version":"1.0","type":"link"}