{"product_id":"proteintech-31846-1-ap","title":"Proteintech, 31846-1-AP, GPR158 Polyclonal antibody","description":"Size: 20ul \/ 150ul\nThe GPR158 (31846-1-AP) by Proteintech is a Polyclonal antibody targeting GPR158 in WB, ELISA applications with reactivity to human samples\n31846-1-AP targets GPR158 in WB, ELISA applications and shows reactivity with human samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: HEK-293T cells, HeLa cells\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:500-1:2000\n\u003cb\u003eBackground Information\u003c\/b\u003e\nG protein-coupled receptors (GPCR) are the largest family of proteins encoded in mammalian genomes that detect extracellular signals to program cellular response, which are essential to understanding physiology, disease, and drug development (PMID: 29249361; 29298813). G protein-coupled receptor 158 (GPR158, also known as mGlyR) is a class C orphan GPCR prominently expressed in brain tissue, where it controls synapse formation and function (PMID: 22689652; 34793198). It can transduce signals by coupling to the regulator of protein signaling (RGS) proteins and be related to the development of major depressive disorder and prostate cancer (PMID: 36996198; 29419376; 25693195).\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human\nHost \/ Isotype: Rabbit \/ IgG\nClass: Polyclonal\nType: Antibody\nImmunogen: CatNo: Ag34602 Product name: Recombinant human GPR158 protein Source: e coli. -derived, PET28a Tag: 6*His Domain: 24-417 aa of BC157124 Sequence: ASRDPQGRPDSPRERTPKGKPHAQQPGRASASDSSAPWSRSTDGTILAQKLAEEVPMDVASYLYTGDSHQLKRANCSGRYELAGLPGKWPALASAHPSLHRALDTLTHATNFLNVMLQSNKSREQNLQDDLDWYQALVWSLLEGEPSISRAAITFSTDSLSAPAPQVFLQATREESRILLQDLSSSAPHLANATLETEWFHGLRRKWRPHLHRRGPNQGPRGLGHSWRRKDGLGGDKSHFKWSPPYLECENGSYKPGWLVTLSSAIYGLQPNLVPEFRGVMKVDINLQKVDIDQCSSDGWFSGTHKCHLNNSECMPIKGLGFVLGAYECICKAGFYHPGVLPVNNFRRRGPDQHISGSTKDVSEEAYVCLPCREGCPFCADDSPCFVQEDKYLR Predict reactive species\nFull Name: G protein-coupled receptor 158\nCalculated Molecular Weight: 135 kDa\nObserved Molecular Weight: 150 kDa\nGenBank Accession Number: BC157124\nGene Symbol: GPR158\nGene ID (NCBI): 57512\nRRID: AB_3670127\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Antigen affinity Purification\nUNIPROT ID: Q5T848\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46887656882345,"sku":"31846-1-AP","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/proteintech-31846-1-ap","provider":"Iright","version":"1.0","type":"link"}