{"product_id":"proteintech-32115-1-ap","title":"Proteintech, 32115-1-AP, EFCAB4A Polyclonal antibody","description":"Size: 20ul \/ 150ul\nThe EFCAB4A (32115-1-AP) by Proteintech is a Polyclonal antibody targeting EFCAB4A in WB, ELISA applications with reactivity to human samples\n32115-1-AP targets EFCAB4A in WB, ELISA applications and shows reactivity with human samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: LNCaP cells\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:1000-1:6000\n\u003cb\u003eBackground Information\u003c\/b\u003e\nEFCAB4A (EF-hand calcium-binding domain-containing protein 4A), also known as CRACR2B (calcium release-activated calcium channel regulator 2B), is a calcium-binding protein containing EF-hand structural domain. EFCAB4A is thought to play a key role in calcium bank-manipulated calcium endocytosis (SOCE) in T cells by regulating activation of CRAC (calcium release-activated calcium channel) channels. This protein may perform a similar function to EFCAB4B, which acts as a cytoplasmic calcium sensor that forms a complex with ORAI1 and STIM1 in the region of the junction between the endoplasmic reticulum and the plasma membrane. The EFCAB4A protein contains two EF-hand structural domains, which may be involved in calcium bank-manipulated calcium endocytosis.\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human\nHost \/ Isotype: Rabbit \/ IgG\nClass: Polyclonal\nType: Antibody\nImmunogen: CatNo: Ag37031 Product name: Recombinant human EFCAB4A protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 100-255 aa of BC033196 Sequence: SAQGANPCRTPEETFESGGLDVQGTAGSLDEEEEEEERFHTVLEQLGVAPVLGEQRAVRTLWARLQRERPELLGSFEDVLIRASACLEEAARERDGLEQALRRRESEHEREVRALYEETEQLREQSRRPPSQNFARGERRSRLELELQIREQDLER Predict reactive species\nFull Name: EF-hand calcium binding domain 4A\nObserved Molecular Weight: 50 kDa\nGenBank Accession Number: BC033196\nGene Symbol: EFCAB4A\nGene ID (NCBI): 283229\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Antigen affinity Purification\nUNIPROT ID: Q8N4Y2\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46887420166313,"sku":"32115-1-AP","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/proteintech-32115-1-ap","provider":"Iright","version":"1.0","type":"link"}