{"product_id":"proteintech-33098-1-ap","title":"Proteintech, 33098-1-AP, Apcdd1 Polyclonal antibody","description":"Size: 20ul \/ 150ul\nThe Apcdd1 (33098-1-AP) by Proteintech is a Polyclonal antibody targeting Apcdd1 in WB, IP, ELISA applications with reactivity to mouse, rat samples\n33098-1-AP targets Apcdd1 in WB, IP, ELISA applications and shows reactivity with mouse, rat samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: mouse skin tissue, rat skin tissue\nPositive IP detected in: mouse skin tissue\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:500-1:2000\nImmunoprecipitation (IP): IP : 0.5-4.0 ug for 1.0-3.0 mg of total protein lysate\n\u003cb\u003eBackground Information\u003c\/b\u003e\nAPCDD1 encodes a membrane-associated Wnt inhibitor that modulates β-catenin signaling during epithelial, vascular, and neural development. Anchored by a GPI linkage, APCDD1 binds Wnt components at the cell surface to restrict pathway activation and maintain tissue polarity. Dysregulation or mutation of APCDD1 contributes to hereditary hair loss, tumor progression, and vascular defects, underscoring its importance as a fine-tuner of Wnt-driven morphogenesis and homeostasis. (PMID: 32320685)\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: mouse, rat\nHost \/ Isotype: Rabbit \/ IgG\nClass: Polyclonal\nType: Antibody\nImmunogen: CatNo: Eg2690 Product name: Recombinant Mouse APCDD1 protein (rFc Tag) Source: mammalian cells -derived, V37 Tag: C-rFc Domain: 27-492 aa of NM_133237.3 Sequence: LLHPDSRSHPRSLEKSAWRAFKESQCHHMLKHLHNGARITVQMPPTIEGHWVSTGCEVRSGPEFMTRSYRFYNNNTFKAYQFYYGSNRCTNPTYTLIIRGKIRLRQASWIIRGGTEADYQLHGVQVICHTEAVAEQLSRLVNRTCPGFLAPGGPWVQDVAYDLWQEESNHECTKAVNFAMHELQLIRVEKQYPHHSLDHLVEELFLGDIHTDATQRVFYRPSSYQPPLQNAKNHNHACIACRIIFRSDEHHPPILPPKADLTIGLHGEWVSQRCEVRPEVLFLTRHFIFHDNNNTWEGHYYHYSDPVCKHPTFTIYARGRYSRGVLSSKVMGGTEFVFKVNHMKVTPMDAATASLLNVFSGNECGAEGSWQVGIQQDVTHTNGCVALGIKLPHTEYEIFKMEQDTRGRYLLFNGQRPSDGSSPDRPEKRATSYQMPLVQCASSSPRAEELLEDSQGHLYGRAAGRT Predict reactive species\nFull Name: adenomatosis polyposis coli down-regulated 1\nCalculated Molecular Weight: 59 kDa\nObserved Molecular Weight: 50 kDa\nGenBank Accession Number: NM_133237.3\nGene Symbol: Apcdd1\nGene ID (NCBI): 494504\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Antigen affinity Purification\nUNIPROT ID: Q3U128\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46884975018153,"sku":"33098-1-AP","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/proteintech-33098-1-ap","provider":"Iright","version":"1.0","type":"link"}