{"product_id":"proteintech-33859-1-ap","title":"Proteintech, 33859-1-AP, PID1 Polyclonal antibody","description":"Size: 20ul \/ 150ul\nThe PID1 (33859-1-AP) by Proteintech is a Polyclonal antibody targeting PID1 in WB, ELISA applications with reactivity to human, rat samples\n33859-1-AP targets PID1 in WB, ELISA applications and shows reactivity with human, rat samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: rat liver tissue\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:500-1:1000\n\u003cb\u003eBackground Information\u003c\/b\u003e\nPID1 is a cytoplasmic PTB-domain adaptor that negatively regulates insulin and IGF1 signaling, modulating AKT activity, glucose uptake, and mitochondrial function. Enriched in muscle, adipose tissue, and liver, PID1 promotes insulin resistance, impacts lipid handling, and contributes to metabolic disease. Its dysregulation also influences tumor metabolism and stress responses, underscoring PID1 as an important node linking growth factor signaling, energy homeostasis, and pathophysiology.\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human, rat\nHost \/ Isotype: Rabbit \/ IgG\nClass: Polyclonal\nType: Antibody\nImmunogen: CatNo: Ag40871 Product name: Recombinant human PID1 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 1-168 aa of BC040164 Sequence: MWQPATERLQVTYLGKVSTTGMQFLSGCTEKPVIELWKKHTLAREDVFPANALLEIRPFQVWLHHLDHKGEATVHMDTFQVARIAYCTADHNVSPNIFAWVYREINDDLSYQMDCHAVECESKLEAKKLAHAMMEAFRKTFHSMKSDGRIHSNSSSEEVSQELESDDG Predict reactive species\nFull Name: phosphotyrosine interaction domain containing 1\nCalculated Molecular Weight: 168 aa, 19 kDa\nObserved Molecular Weight: 25 kDa, 28 kDa\nGenBank Accession Number: BC040164\nGene Symbol: PID1\nGene ID (NCBI): 55022\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Antigen affinity Purification\nUNIPROT ID: Q7Z2X4\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46887762493609,"sku":"33859-1-AP","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/proteintech-33859-1-ap","provider":"Iright","version":"1.0","type":"link"}