{"product_id":"proteintech-33950-1-ap","title":"Proteintech, 33950-1-AP, JPH2 Polyclonal antibody","description":"Size: 20ul \/ 150ul\nThe JPH2 (33950-1-AP) by Proteintech is a Polyclonal antibody targeting JPH2 in WB, ELISA applications with reactivity to human samples\n33950-1-AP targets JPH2 in WB, ELISA applications and shows reactivity with human samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: Caco-2 cells\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:1000-1:6000\n\u003cb\u003eBackground Information\u003c\/b\u003e\nThe JPH2 protein (Junctophilin-2) is a key structural protein specifically expressed in cardiac and skeletal muscles. It acts as a \"physical bridge\" between the endoplasmic reticulum and the cell membrane (the transverse tubule system), ensuring the precise spatial positioning and stability of the calcium ion release units (calcium sparks) necessary for excitation-contraction coupling by forming connection complexes. Abnormal function of this protein is closely related to various cardiac diseases such as cardiac hypertrophy, heart failure, and arrhythmia.\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human\nHost \/ Isotype: Rabbit \/ IgG\nClass: Polyclonal\nType: Antibody\nImmunogen: CatNo: Eg5481 Product name: Recombinant human JPH2 protein Source: mammalian cells -derived, V37 Tag: C-rFc Domain: 1-672 aa of NM_020433.4 Sequence: MSGGRFDFDDGGAYCGGWEGGKAHGHGLCTGPKGQGEYSGSWNFGFEVAGVYTWPSGNTFEGYWSQGKRHGLGIETKGRWLYKGEWTHGFKGRYGIRQSSSSGAKYEGTWNNGLQDGYGTETYADGGTYQGQFTNGMRHGYGVRQSVPYGMAVVVRSPLRTSLSSLRSEHSNGTVAPDSPASPASDGPALPSPAIPRGGFALSLLANAEAAARAPKGGGLFQRGALLGKLRRAESRTSVGSQRSRVSFLKSDLSSGASDAASTASLGEAAEGADEAAPFEADIDATTTETYMGEWKNDKRSGFGVSERSSGLRYEGEWLDNLRHGYGCTTLPDGHREEGKYRHNVLVKDTKRRMLQLKSNKVRQKVEHSVEGAQRAAAIARQKAEIAASRTSHAKAKAEAAEQAALAANQESNIARTLARELAPDFYQPGPEYQKRRLLQEILENSESLLEPPDRGAGAAGLPQPPRESPQLHERETPRPEGGSPSPAGTPPQPKRPRPGVSKDGLLSPGAWNGEPSGEGSRSVTPSEGAGRRSPARPATERMAIEALQAPPAPSREPEVALYQGYHSYAVRTTPPEPPPFEDQPEPEVSGSESAPSSPATAPLQAPTLRGPEPARETPAKLEPKPIIPKAEPRAKARKTEARGLTKAGAKKKARKEAALAAEAEVEVEEVP Predict reactive species\nFull Name: junctophilin 2\nCalculated Molecular Weight: 74 kDa\nObserved Molecular Weight: 98 kDa\nGenBank Accession Number: NM_020433.4\nGene Symbol: JPH2\nGene ID (NCBI): 57158\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Antigen affinity Purification\nUNIPROT ID: Q9BR39-1\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46887689388201,"sku":"33950-1-AP","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/proteintech-33950-1-ap","provider":"Iright","version":"1.0","type":"link"}