{"product_id":"proteintech-55224-1-ap","title":"Proteintech, 55224-1-AP, HCN4 Polyclonal antibody","description":"Size: 20ul \/ 150ul\nThe HCN4 (55224-1-AP) by Proteintech is a Polyclonal antibody targeting HCN4 in WB, ELISA applications with reactivity to human, mouse, rat samples\n55224-1-AP targets HCN4 in WB, ELISA applications and shows reactivity with human, mouse, rat samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: mouse brain tissue, rat brain tissue\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:1000-1:8000\n\u003cb\u003eBackground Information\u003c\/b\u003e\nHCN4 belongs to the potassium channel HCN family.  It hyperpolarization-activated ion channel with very slow activation and inactivation exhibiting weak selectivity for potassium over sodium ions. HCN4 may contribute to the native pacemaker currents in heart (If) and in neurons (Ih). It is activated by cAMP. HCN4 may mediate responses to sour stimuli. (PMID:10228147). Defects in HCN4 are a cause of sick sinus syndrome type 2 (SSS2). Defects in HCN4 are the cause of Brugada syndrome type 8 (BRS8). This antibody is specific to HCN4.\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human, mouse, rat\nCited Reactivity: human, mouse, rat, hamster\nHost \/ Isotype: Rabbit \/ IgG\nClass: Polyclonal\nType: Antibody\nImmunogen: Peptide Predict reactive species\nFull Name: hyperpolarization activated cyclic nucleotide-gated potassium channel 4\nCalculated Molecular Weight: 129 kDa\nObserved Molecular Weight: 140-160 kDa\nGenBank Accession Number: NM_005477\nGene Symbol: HCN4\nGene ID (NCBI): 10021\nRRID: AB_11182714\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Antigen affinity purification\nUNIPROT ID: Q9Y3Q4\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46868967325865,"sku":"55224-1-AP","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/proteintech-55224-1-ap","provider":"Iright","version":"1.0","type":"link"}