{"product_id":"proteintech-55323-1-ap","title":"Proteintech, 55323-1-AP, TNKS1BP1 Polyclonal antibody","description":"Size: 20ul \/ 150ul\nThe TNKS1BP1 (55323-1-AP) by Proteintech is a Polyclonal antibody targeting TNKS1BP1 in WB, ELISA applications with reactivity to human samples\n55323-1-AP targets TNKS1BP1 in WB, ELISA applications and shows reactivity with human samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: HeLa cells, HepG2 cells,  L02 cells,  MCF-7 cells\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:500-1:2000\n\u003cb\u003eBackground Information\u003c\/b\u003e\nTNKS1BP1, also known as TAB182, is a member of the poly(ADP-ribose) polymerase (PARP) superfamily. It is an anchor polymerase 1 (Tankyrase1) binding protein with a molecular weight of 182 kDa and is widely distributed throughout the cell, including the cell membrane, cytoplasm, and nucleus. TNKS1BP1 functions in both telomere maintenance and DNA damage response. TNKS1BP1 can compete with TRF1 to bind to the multiple binding sites of tankyrase1, potentially interfering with the transport of tankyrase1 from cytoplasm to nucleus and its localization in telomeres, which affects the stability of telomeres (PMID: 28058814, PMID: 39019859, PMID: 39113018).\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human\nHost \/ Isotype: Rabbit \/ IgG\nClass: Polyclonal\nType: Antibody\nImmunogen: Peptide Predict reactive species\nFull Name: tankyrase 1 binding protein 1, 182kDa\nCalculated Molecular Weight: 182 kDa\nObserved Molecular Weight: 182 kDa\nGenBank Accession Number: NM_033396\nGene Symbol: TNKS1BP1\nGene ID (NCBI): 85456\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Antigen affinity purification\nUNIPROT ID: Q9C0C2\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46887834779817,"sku":"55323-1-AP","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/proteintech-55323-1-ap","provider":"Iright","version":"1.0","type":"link"}