{"product_id":"proteintech-65058-1-ig","title":"Proteintech, 65058-1-Ig, Anti-Mouse CD31 (390)","description":"Size: 100ug \/ 500ug\nThe CD31 (65058-1-Ig) by Proteintech is a Monoclonal antibody targeting CD31 in IF\/ICC, FC applications with reactivity to mouse samples\n65058-1-Ig targets CD31 in IF\/ICC, FC applications and shows reactivity with mouse samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive IF\/ICC detected in: bEnd.3 cells\nPositive FC detected in: mouse splenocytes\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nImmunofluorescence (IF)\/ICC: IF\/ICC : 1:50-1:500\nFlow Cytometry (FC): FC : 0.5 ug per 10^6 cells in 100 μl suspension\n\u003cb\u003eBackground Information\u003c\/b\u003e\nPlatelet endothelial cell adhesion molecule-1 (PECAM-1, CD31) is a member of the immunoglobulin gene superfamily of cell adhesion molecules. CD31 is a transmembrane glycoprotein that is highly expressed on the surface of the endothelium, making up a large portion of its intracellular junctions. PECAM-1 is also present on the surface of hematopoietic cells and immune cells including platelets, monocytes, neutrophils, natural killer cells, megakaryocytes and some types of T-cell (PMID: 9011572). As well as its role in cell-cell adhesion, PECAM-1 functions as a signaling receptor, and is involved in important physiological events such as nitric oxide production, regulation of T-cell immunity and tolerance, leukocyte transendothelial migration and inflammation and angiogenesis (PMID: 21183735; 20978210; 17872453; 20634489).\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: mouse\nCited Reactivity: mouse\nHost \/ Isotype: Rat \/ IgG2a, kappa\nClass: Monoclonal\nType: Antibody\nImmunogen: C3H\/HeJ mouse hematopoietic progenitor cell line 32D Predict reactive species\nFull Name: platelet\/endothelial cell adhesion molecule 1\nGenBank Accession Number: BC008519\nGene Symbol: CD31\nGene ID (NCBI): 18613\nRRID: AB_2918366\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Affinity purification\nUNIPROT ID: Q08481\nStorage Buffer: PBS with 0.09% sodium azide, pH 7.3.\nStorage Conditions: Store at 2-8°C. Stable for one year after shipment.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46887997440169,"sku":"65058-1-Ig","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/proteintech-65058-1-ig","provider":"Iright","version":"1.0","type":"link"}