{"product_id":"proteintech-65077-1-ig","title":"Proteintech, 65077-1-Ig, Anti-Mouse CD3 (17A2)","description":"Size: 500ug\nThe CD3 (65077-1-Ig) by Proteintech is a Monoclonal antibody targeting CD3 in FC applications with reactivity to mouse samples\n65077-1-Ig targets CD3 in FC, FC (Intra) applications and shows reactivity with mouse samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive FC detected in: C57BL\/6 mouse splenocytes\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nFlow Cytometry (FC): FC : 0.5 ug per 10^6 cells in 100 μl suspension\n\u003cb\u003eBackground Information\u003c\/b\u003e\nCD3 is a multimeric protein associated with the T-cell receptor (TCR) to form a complex involved in antigen recognition and signal transduction (PMID: 15885124). CD3 is composed of CD3γ, δ, ε, and ζ chains (PMID: 1826255). It is expressed by thymocytes in a developmentally regulated manner, T cells, and some NK cells (PMID: 3289580). The TCR recognizes antigens bound to major histocompatibility complex (MHC) molecules. TCR-mediated peptide-MHC recognition is transmitted to the CD3 complex, leading to the intracellular signal transduction (PMID: 11985657).\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: mouse\nCited Reactivity: mouse\nHost \/ Isotype: Rat \/ IgG2b, kappa\nClass: Monoclonal\nType: Antibody\nImmunogen: γδTCR-positive T-T hybridoma D1 Predict reactive species\nFull Name: CD3 antigen, epsilon polypeptide\nGenBank Accession Number: BC098236\nGene Symbol: CD3ε\nGene ID (NCBI): 12501\nRRID: AB_2918381\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Affinity purification\nUNIPROT ID: P22646\nStorage Buffer: PBS with 0.09% sodium azide, pH 7.3.\nStorage Conditions: Store at 2-8°C. Stable for one year after shipment.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46888054554793,"sku":"65077-1-Ig","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/proteintech-65077-1-ig","provider":"Iright","version":"1.0","type":"link"}