{"product_id":"proteintech-65103-1-ig","title":"Proteintech, 65103-1-Ig, Anti-Human CD40 (G28.5)","description":"Size: 100ug \/ 500ug\nThe CD40 (65103-1-Ig) by Proteintech is a Monoclonal antibody targeting CD40 in FC applications with reactivity to Human samples\n65103-1-Ig targets CD40 in FC applications and shows reactivity with Human samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive FC detected in: human PBMCs\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nFlow Cytometry (FC): FC : 0.2 ug per 10^6 cells in 100 μl suspension\n\u003cb\u003eBackground Information\u003c\/b\u003e\nCD40, also named as TNFRSF5 and Bp50, is a type I transmembrane protein that belongs to the tumor necrosis factor-R (TNF-R) family (PMID: 10647992). CD40 is expressed on B cells, dendritic cells (DCs), monocytes, platelets, and macrophages as well as by non-hematopoietic cells such as myofibroblasts, fibroblasts, epithelial, and endothelial cells (PMID: 19426221). It is a receptor for TNFSF5\/CD40LG. CD40L\/CD40 interactions are essential for immunoglobulin (Ig) isotype switching, germinal center formation and the development of B cell memory (PMID: 7516405; 11675497).\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: Human\nHost \/ Isotype: Mouse \/ IgG1, kappa\nClass: Monoclonal\nType: Antibody\nImmunogen: N\/A Predict reactive species\nFull Name: CD40 molecule, TNF receptor superfamily member 5\nCalculated Molecular Weight: 277 aa, 31 kDa\nGenBank Accession Number: BC012419\nGene Symbol: CD40\nGene ID (NCBI): 958\nENSEMBL Gene ID: ENSG00000101017\nRRID: AB_2881471\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Affinity purification\nUNIPROT ID: P25942\nStorage Buffer: PBS with 0.09% sodium azide, pH 7.3.\nStorage Conditions: Store at 2-8°C. Stable for one year after shipment.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46888091386025,"sku":"65103-1-Ig","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/proteintech-65103-1-ig","provider":"Iright","version":"1.0","type":"link"}