{"product_id":"proteintech-65163-1-ig","title":"Proteintech, 65163-1-Ig, Anti-Human CD42b (AK2)","description":"Size: 100ug \/ 500ug\nThe CD42b (65163-1-Ig) by Proteintech is a Monoclonal antibody targeting CD42b in FC applications with reactivity to Human samples\n65163-1-Ig targets CD42b in FC applications and shows reactivity with Human samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive FC detected in: human peripheral blood platelets\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nFlow Cytometry (FC): FC : 0.2 ug per 10^6 cells in 100 μl suspension\n\u003cb\u003eBackground Information\u003c\/b\u003e\nCD42b, also known as platelet glycoprotein Ib alpha chain (GPIb alpha), is a type I transmembrane glycoprotein of 135-145 kDa (PMID: 2656709). It is expressed on platelets and megakaryocytes. CD42b and CD42c (GPIb beta) are linked by a disulphide bond to form GPIb (PMID: 7660135). GPIb forms a noncovalent complex with CD42a (GPIX) and CD42d (GPV) and acts as a receptor for von Willebrand factor (vWF) and thrombin (PMID: 7660135; 3759960). The GPIb-V-IX complex mediates vWF-dependent platelet adhesion to blood vessels. Defects in the expression of CD42b result in Bernard-Soulier syndromes and platelet-type von Willebrand disease (PMID: 9371310).\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: Human\nHost \/ Isotype: Mouse \/ IgG1\nClass: Monoclonal\nType: Antibody\nImmunogen: Human platelets Predict reactive species\nFull Name: glycoprotein Ib (platelet), alpha polypeptide\nCalculated Molecular Weight: 626 aa, 69 kDa\nGenBank Accession Number: BC027955\nGene Symbol: CD42b\nGene ID (NCBI): 2811\nENSEMBL Gene ID: ENSG00000185245\nRRID: AB_2881480\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Protein G purification\nUNIPROT ID: P07359\nStorage Buffer: PBS with 0.09% sodium azide, pH 7.3.\nStorage Conditions: Store at 2-8°C. Stable for one year after shipment.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46888092041385,"sku":"65163-1-Ig","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/proteintech-65163-1-ig","provider":"Iright","version":"1.0","type":"link"}