{"product_id":"proteintech-65188-1-ig","title":"Proteintech, 65188-1-Ig, Anti-Human CD314\/NKG2D (1D11)","description":"Size: 100ug \/ 500ug\nThe CD314\/NKG2D (65188-1-Ig) by Proteintech is a Monoclonal antibody targeting CD314\/NKG2D in FC applications with reactivity to Human samples\n65188-1-Ig targets CD314\/NKG2D in FC applications and shows reactivity with Human samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive FC detected in: human PBMCs\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nFlow Cytometry (FC): FC : 0.2 ug per 10^6 cells in 100 μl suspension\n\u003cb\u003eBackground Information\u003c\/b\u003e\nCD314, also known as NKG2D or Killer cell lectin-like receptor subfamily K member 1 (KLRK1), is a type II lectin-like transmembrane stimulatory receptor (PMID: 8436421). In humans, it is expressed on NK cells, gamma delta T cells, and CD8+ alpha beta T cells (PMID: 10426993). Various families of cell surface ligands have been identified, including the MICA\/MICB and ULBP proteins (PMID: 12150888). CD314 is involved in both innate and adaptive immunities, and the NKG2D\/NKG2DL pathway involves multiple effector cell types for controlling tumor progression (PMID: 31720075).\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: Human\nHost \/ Isotype: Mouse \/ IgG1, kappa\nClass: Monoclonal\nType: Antibody\nImmunogen: NKL cell line Predict reactive species\nFull Name: killer cell lectin-like receptor subfamily K, member 1\nCalculated Molecular Weight: 25 kDa\nGenBank Accession Number: BC039836\nGene Symbol: KLRK1\nGene ID (NCBI): 22914\nRRID: AB_2918459\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Purified by protein-A affinity chromatography\nUNIPROT ID: P26718\nStorage Buffer: PBS with 0.09% sodium azide, pH 7.3.\nStorage Conditions: Store at 2-8°C. Stable for one year after shipment.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46888089813161,"sku":"65188-1-Ig","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/proteintech-65188-1-ig","provider":"Iright","version":"1.0","type":"link"}