{"product_id":"proteintech-65221-1-ig","title":"Proteintech, 65221-1-Ig, Anti-Mouse B7-H3\/CD276 (MJ18)","description":"Size: 100ug \/ 500ug\nThe B7-H3\/CD276 (65221-1-Ig) by Proteintech is a Monoclonal antibody targeting B7-H3\/CD276 in FC applications with reactivity to mouse samples\n65221-1-Ig targets B7-H3\/CD276 in FC applications and shows reactivity with mouse samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive FC detected in: mouse peritoneal macrophages\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nFlow Cytometry (FC): FC : 1 ug per 10^6 cells in 100 μl suspension\n\u003cb\u003eBackground Information\u003c\/b\u003e\nCD276 (also known as B7-H3) is a type I transmembrane protein expressed on many tissues and cell types. CD276 is a 100-kDa glycoprotein that belongs to the B7 immunoregulatory family and participates in the regulation of T-cell-mediated immune response probably by functioning as both a T cell costimulator and coinhibitor (PMID: 25567370; 20696859). Overexpressed on a wide range of human solid cancers, CD276 has been implicated in cancer progression and metastasis and becomes an attractive target for cancer immunotherapy (PMID: 27208063).\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: mouse\nHost \/ Isotype: Rat \/ IgG1, kappa\nClass: Monoclonal\nType: Antibody\nImmunogen: Mouse IgG2a Fc-CD276 (aa 1-242) fusion protein Predict reactive species\nFull Name: CD276 antigen\nGenBank Accession Number: BC019436\nGene Symbol: Cd276\nGene ID (NCBI): 102657\nRRID: AB_2935144\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Protein G purification\nUNIPROT ID: Q8VE98\nStorage Buffer: PBS with 0.09% sodium azide, pH 7.3.\nStorage Conditions: Store at 2-8°C. Stable for one year after shipment.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46888095940777,"sku":"65221-1-Ig","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/proteintech-65221-1-ig","provider":"Iright","version":"1.0","type":"link"}