{"product_id":"proteintech-65233-1-ig","title":"Proteintech, 65233-1-Ig, Anti-Human LRP1 (5A6)","description":"Size: 100ug \/ 500ug\nThe LRP1 (65233-1-Ig) by Proteintech is a Monoclonal antibody targeting LRP1 in FC applications with reactivity to Human samples\n65233-1-Ig targets LRP1 in FC applications and shows reactivity with Human samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive FC detected in: U-87 MG cells\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nFlow Cytometry (FC): FC : 1 ug per 10^6 cells in 100 μl suspension\n\u003cb\u003eBackground Information\u003c\/b\u003e\nLRP1 (Prolow-density lipoprotein receptor-related protein 1), also known as A2MR, APOER and CD91, is a type I transmembrane protein that belongs to the LDLR family. LRP1 is synthesized as a transmembrane glycosylated precursor of 600 kDa, and is subsequently cleaved to generate a large 515-kDa N-terminal extracellular subunit and an 85-kDa C-terminal transmembrane subunit, which are noncovalently associated with one another (PMID: 2112085; 8546712). LRP1 is a multifunctional receptor involved in the clearance of a large number of diverse ligands and modulating various cellular processes. LRP1 is implicated in conditions such as atherosclerosis, cancer and neurodegenerative diseases (PMID: 28381441).\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: Human\nHost \/ Isotype: Mouse \/ IgG2b\nClass: Monoclonal\nType: Antibody\nImmunogen: Full length native protein (purified) Predict reactive species\nFull Name: low density lipoprotein-related protein 1 (alpha-2-macroglobulin receptor)\nCalculated Molecular Weight: 505 kDa\nGenBank Accession Number: BC045107\nGene Symbol: LRP1\nGene ID (NCBI): 4035\nRRID: AB_3084909\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Affinity purification\nUNIPROT ID: Q07954\nStorage Buffer: PBS with 0.09% sodium azide, pH 7.3.\nStorage Conditions: Store at 2-8°C. Stable for one year after shipment.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46888095645865,"sku":"65233-1-Ig","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/proteintech-65233-1-ig","provider":"Iright","version":"1.0","type":"link"}