{"product_id":"proteintech-65292-1-ig","title":"Proteintech, 65292-1-Ig, O-GlcNAc Monoclonal antibody","description":"Size: 20ul \/ 150ul\nThe O-GlcNAc (65292-1-Ig) by Proteintech is a Monoclonal antibody targeting O-GlcNAc in WB applications with reactivity to n\/a samples\n65292-1-Ig targets O-GlcNAc in WB applications and shows reactivity with n\/a samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: HeLa cells\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:2000-20000\n\u003cb\u003eBackground Information\u003c\/b\u003e\nO-GlcNAc (O-linked β-N-acetylgulcosamine) is a post-translational modification of serine and threonine residues in proteins. O-GlcNAc modification is abundant in all multicellular eukaryotes, exclusively found on nuclear and cytoplasmic proteins rather than membrane proteins and secretory proteins (PMID: 11269319; 10924527). O-GlcNAc is attached to the protein backbone by enzymatic addition of the N-acetylgulcosamine (GlcNAc) moiety of uridine 5′-diphospho (UDP)-GlcNAc to the hydroxyl oxygen of serines or threonines by the O-linked β-N-acetylgulcosamine transferase (OGT). O-GlcNAc glycosylated proteins can be reversiblely deglycosylated by β-D-N-acetylgulcosaminase (O-GlcNAcase) (PMID: 21526146). O-GlcNAc modification couples many biological processes and plays important roles in development, normal physiology and physiopathology (PMID: 32349769).\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: n\/a\nHost \/ Isotype: Mouse \/ IgM\nClass: Monoclonal\nType: Antibody\nImmunogen: N\/A Predict reactive species\nFull Name: O-GlcNAc\nRRID: AB_3670285\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Thiophilic affinity chromatograph\nStorage Buffer: PBS with 0.09% sodium azide, pH 7.3.\nStorage Conditions: Store at 2-8°C. Stable for one year after shipment. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46888307490985,"sku":"65292-1-Ig","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/proteintech-65292-1-ig","provider":"Iright","version":"1.0","type":"link"}