{"product_id":"proteintech-65295-1-ig","title":"Proteintech, 65295-1-Ig, Anti-Human CD63 (H5C6)","description":"Size: 100ug\nThe CD63 (65295-1-Ig) by Proteintech is a Monoclonal antibody targeting CD63 in FC applications with reactivity to human samples\n65295-1-Ig targets CD63 in FC applications and shows reactivity with human samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive FC detected in: thrombin-activated human peripheral blood platelets\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nFlow Cytometry (FC): FC : 0.2 ug per 10^6 cells in 100 μl suspension\n\u003cb\u003eBackground Information\u003c\/b\u003e\nCD63 is a 30-60 kDa lysosomal membrane protein that belongs to the tetraspanin family. This protein plays many important roles in immuno-physiological functions. It mediates signal transduction events that play a role in the regulation of cell development, activation, growth, and motility. CD63 is expressed on activated platelets, thus it may function as a blood platelet activation marker. CD63 is a lysosomal membrane glycoprotein that is translocated to plasma membrane after platelet activation. The CD63 tetraspanin is highly expressed in the early stages of melanoma and decreases in advanced lesions, suggesting it as a possible suppressor of tumor progression. Deficiency of this protein is associated with Hermansky-Pudlak syndrome.\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human\nHost \/ Isotype: Mouse \/ IgG1, kappa\nClass: Monoclonal\nType: Antibody\nImmunogen: Human splenic adherent cells Predict reactive species\nFull Name: CD63 molecule\nGenBank Accession Number: BC013017\nGene Symbol: CD63\nGene ID (NCBI): 967\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Affinity purification\nUNIPROT ID: P08962\nStorage Buffer: PBS with 0.09% sodium azide, pH 7.3.\nStorage Conditions: Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46888092729513,"sku":"65295-1-Ig","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/proteintech-65295-1-ig","provider":"Iright","version":"1.0","type":"link"}