{"product_id":"proteintech-65611-1-mr","title":"Proteintech, 65611-1-MR, Anti-Human ALCAM (3A6) Mouse IgG2a Recombinant Antibody","description":"Size: 100ug\nThe ALCAM (65611-1-MR) by Proteintech is a Recombinant antibody targeting ALCAM in IF\/ICC, FC applications with reactivity to human samples\n65611-1-MR targets ALCAM in IF\/ICC, FC applications and shows reactivity with human samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive IF\/ICC detected in: hTERT-RPE1 cells\nPositive FC detected in: PHA treated human PBMCs\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nImmunofluorescence (IF)\/ICC: IF\/ICC : 1:200-1:800\nFlow Cytometry (FC): FC : 0.25 ug per 10^6 cells in 100 μl suspension\n\u003cb\u003eBackground Information\u003c\/b\u003e\nActivated leukocyte cell adhesion molecule (ALCAM, also known as CD166) is a cell adhesion molecule that belongs to the immunoglobulin superfamily. It is involved in cell-cell adhesion through homophilic and heterophilic (to CD6) interactions. ALCAM is widely expressed in a variety of normal tissues and cell types, including activated T cells and monocytes, epithelial cells, fibroblasts, neuronal cells, hepatocytes, and bone marrow mesenchymal stem cells (PMID: 7760007; 25221999). Altered ALCAM expression has been associated with the differentiation state and progression in some neoplasms including melanoma, prostate, colorectal, and breast cancers (PMID: 20461761; 18172759).\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human\nHost \/ Isotype: Mouse \/ IgG2a\nClass: Recombinant\nType: Antibody\nImmunogen: Cultured human thymic epithelial cells Predict reactive species\nFull Name: activated leukocyte cell adhesion molecule\nCalculated Molecular Weight: 105 kDa\nGenBank Accession Number: BC057809\nGene Symbol: ALCAM\nGene ID (NCBI): 214\nRRID: AB_3670358\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Protein A purification\nUNIPROT ID: Q13740\nStorage Buffer: PBS with 0.09% sodium azide, pH 7.3.\nStorage Conditions: Store at 2-8°C. Stable for one year after shipment.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46888538374313,"sku":"65611-1-MR","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/proteintech-65611-1-mr","provider":"Iright","version":"1.0","type":"link"}