{"product_id":"proteintech-65622-1-mr","title":"Proteintech, 65622-1-MR, Anti-Human CD35 (E11) Mouse IgG2a Recombinant Antibody","description":"Size: 100ug\nThe CD35 (65622-1-MR) by Proteintech is a Recombinant antibody targeting CD35 in FC applications with reactivity to human samples\n65622-1-MR targets CD35 in FC applications and shows reactivity with human samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive FC detected in: human PBMCs\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nFlow Cytometry (FC): FC : 0.25 ug per 10^6 cells in 100 μl suspension\n\u003cb\u003eBackground Information\u003c\/b\u003e\nCD35, also known as complement receptor type 1 (CR1) or C3b\/C4b receptor, is a single-chain glycoprotein consisting of 30 repeating homologous protein domains known as short consensus repeats (~60 amino acids each) followed by transmembrane and cytoplasmic domains (PMID: 8765013). CD35 is variably expressed by granulocytes, monocytes, B cells, some T cells, erythrocytes, follicular dendritic cells, Langerhans cells, and glomerular podocytes (PMID: 19004497). CD35 acts as a receptor for C3b and C4b and plays important roles in the regulation of the complement cascade and clearance of immune complexes.\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human\nCited Reactivity: rat\nHost \/ Isotype: Mouse \/ IgG2a\nClass: Recombinant\nType: Antibody\nImmunogen: Human CD35 from Acute monocytic leukemia cells and normal blood monocytes Predict reactive species\nFull Name: complement component (3b\/4b) receptor 1 (Knops blood group)\nCalculated Molecular Weight: 224 kDa\nGenBank Accession Number: NM_000573\nGene Symbol: CR1\nGene ID (NCBI): 1378\nENSEMBL Gene ID: ENSG00000203710\nRRID: AB_3670365\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Protein A purification\nUNIPROT ID: P17927\nStorage Buffer: PBS with 0.09% sodium azide, pH 7.3.\nStorage Conditions: Store at 2-8°C. Stable for one year after shipment.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46888531427497,"sku":"65622-1-MR","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/proteintech-65622-1-mr","provider":"Iright","version":"1.0","type":"link"}