{"product_id":"proteintech-65672-1-tr","title":"Proteintech, 65672-1-TR, Anti-Mouse CD11b (M1\/70) Rat Recombinant Antibody","description":"Size: 100ug\nThe CD11b (65672-1-TR) by Proteintech is a Recombinant antibody targeting CD11b in IF\/ICC, FC applications with reactivity to human, mouse, rabbit, monkey, guinea pig, non-human primates samples\n65672-1-TR targets CD11b in IF\/ICC, FC applications and shows reactivity with human, mouse, rabbit, monkey, guinea pig, non-human primates samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive IF\/ICC detected in: RAW 264.7 cells\nPositive FC detected in: mouse bone marrow cells, rabbit splenocytes\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nImmunofluorescence (IF)\/ICC: IF\/ICC : 1:400-1:1600\nFlow Cytometry (FC): FC : 0.5 ug per 10^6 cells in a 100 µl suspension\n\u003cb\u003eBackground Information\u003c\/b\u003e\nIntegrins are cell adhesion receptors that are heterodimers composed of non-covalently associated α and β subunits (PMID: 9779984). CD11b, also known as Integrin alpha M or CR3A, belongs to the integrin alpha chain family. CD11b forms an α\/β heterodimer with CD18 (integrin β2). CD11b\/CD18 is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles and pathogens (PMID: 9558116; 20008295). CD11b\/CD18 is a receptor for the complement protein fragment iC3b, and is also a receptor for fibrinogen, factor X and ICAM1 (PMID: 2971974; 15485828).\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human, mouse, rabbit, monkey, guinea pig, non-human primates\nHost \/ Isotype: Rat \/ IgG2a\nClass: Recombinant\nType: Antibody\nImmunogen: N\/A Predict reactive species\nFull Name: integrin alpha M\nCalculated Molecular Weight: 127 kDa\nGenBank Accession Number: BC156991\nGene Symbol: CD11b\nGene ID (NCBI): 16409\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Protein A purification\nUNIPROT ID: E9Q604\nStorage Buffer: PBS with 0.09% sodium azide, pH 7.3.\nStorage Conditions: Store at 2-8°C. Stable for one year after shipment.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46888561836201,"sku":"65672-1-TR","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/proteintech-65672-1-tr","provider":"Iright","version":"1.0","type":"link"}