{"product_id":"proteintech-66304-1-ig","title":"Proteintech, 66304-1-Ig, CD47 Monoclonal antibody","description":"Size: 20ul \/ 150ul\nThe CD47 (66304-1-Ig) by Proteintech is a Monoclonal antibody targeting CD47 in WB, IF\/ICC, ELISA applications with reactivity to human samples\n66304-1-Ig targets CD47 in WB, IF\/ICC, ELISA applications and shows reactivity with human samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: SKOV-3 cells, A549 cells,  HT-1080 cells,  Jurkat cells,  NCI-H1299 cells,  HUVEC cells,  K-562 cells,  TF-1 cells,  human placenta tissue,  HeLa cells,  HaCaT cells,  PANC-1 cells,  MDA-MB-231 cells\nPositive IF\/ICC detected in: A549 cells\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:5000-1:50000\nImmunofluorescence (IF)\/ICC: IF\/ICC : 1:200-1:800\n\u003cb\u003eBackground Information\u003c\/b\u003e\nCD47, also known as integrin-associated protein (IAP), is a member of the immunoglobulin superfamily containing a five-pass transmembrane attachment. CD47 is heavily glycosylated and widely expressed by hematopoietic and nonhematopoietic cells. CD47 interacts with several membrane integrins and also acts a receptor for thrombospondin (THBS1). It is involved in a range of cellular processes, including apoptosis, proliferation, adhesion, and migration. CD47 also functions as a ligand for signal regulatory protein-α (SIRPα). Upon binding CD47, SIRPα initiates a signaling cascade that results in the inhibition of phagocytosis.\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human\nCited Reactivity: human, mouse, rat\nHost \/ Isotype: Mouse \/ IgG2b\nClass: Monoclonal\nType: Antibody\nImmunogen: CatNo: Ag14132 Product name: Recombinant human CD47 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 1-150 aa of BC010016 Sequence: MWPLVAALLLGSACCGSAQLLFNKTKSVEFTFCNDTVVIPCFVTNMEAQNTTEVYVKWKFKGRDIYTFDGALNKSTVPTDFSSAKIEVSQLLKGDASLKMDKSDAVSHTGNYTCEVTELTREGETIIELKYRVVSWFSPNENILIVIFPI Predict reactive species\nFull Name: CD47 molecule\nCalculated Molecular Weight: 323 aa, 35 kDa\nObserved Molecular Weight: 50-55 kDa\nGenBank Accession Number: BC010016\nGene Symbol: CD47\nGene ID (NCBI): 961\nRRID: AB_2881687\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Protein A purification\nUNIPROT ID: Q08722\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46887987675305,"sku":"66304-1-Ig","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/proteintech-66304-1-ig","provider":"Iright","version":"1.0","type":"link"}