{"product_id":"proteintech-66369-1-ig","title":"Proteintech, 66369-1-Ig, PGC1a Monoclonal antibody","description":"Size: 20ul \/ 150ul\nThe PGC1a (66369-1-Ig) by Proteintech is a Monoclonal antibody targeting PGC1a in WB, IF\/ICC, ELISA applications with reactivity to human, mouse, rat, pig samples\n66369-1-Ig targets PGC1a in WB, IHC, IF\/ICC, IP, CoIP, ChIP, ELISA applications and shows reactivity with human, mouse, rat, pig samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: pig skeletal muscle tissue, HSC-T6 cells,  rat skeletal muscle tissue,  mouse skeletal muscle tissue\nPositive IF\/ICC detected in: HeLa cells\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:5000-1:50000\nImmunofluorescence (IF)\/ICC: IF\/ICC : 1:1000-1:4000\n\u003cb\u003eBackground Information\u003c\/b\u003e\nPPARGC1A, also named as Peroxisome proliferator-activated receptor gamma coactivator 1-alpha, is a 798 amino acid protein, which Contains 1 RRM (RNA recognition motif) domain and localizes in the nucleus. PPARGC1A is transcriptional coactivator for steroid receptors and nuclear receptors. PPARGC1A can regulate key mitochondrial genes that contribute to the program of adaptive thermogenesis and  plays an essential role in metabolic reprogramming in response to dietary availability through coordination of the expression of a wide array of genes involved in glucose and fatty acid metabolism. PPARGC1A exists an isoform in the liver and the molecular weight of it is 77 kDa. Except for a deletion of 127 amino acids at the N terminus, the protein, termed L-PGC-1 α, is identical to PGC-1.\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human, mouse, rat, pig\nCited Reactivity: human, mouse, rat, pig, monkey, chicken, zebrafish, hamster, goat, ducks\nHost \/ Isotype: Mouse \/ IgG1\nClass: Monoclonal\nType: Antibody\nImmunogen: Peptide Predict reactive species\nFull Name: peroxisome proliferator-activated receptor gamma, coactivator 1 alpha\nCalculated Molecular Weight: 91 kDa\nObserved Molecular Weight: 70 kDa, 100 kDa\nGenBank Accession Number: NM_013261\nGene Symbol: PGC1a\nGene ID (NCBI): 10891\nRRID: AB_2828002\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Protein G purification\nUNIPROT ID: Q9UBK2\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46887967850665,"sku":"66369-1-Ig","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/proteintech-66369-1-ig","provider":"Iright","version":"1.0","type":"link"}