{"product_id":"proteintech-66619-1-ig","title":"Proteintech, 66619-1-Ig, Adiponectin receptor 1 Monoclonal antibody","description":"Size: 20ul \/ 150ul\nThe Adiponectin receptor 1 (66619-1-Ig) by Proteintech is a Monoclonal antibody targeting Adiponectin receptor 1 in WB, ELISA applications with reactivity to Human samples\n66619-1-Ig targets Adiponectin receptor 1 in WB, IHC, ELISA applications and shows reactivity with Human samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: HeLa cells, HEK-293 cells,  L02 cells,  HepG2 cells\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:1000-1:6000\n\u003cb\u003eBackground Information\u003c\/b\u003e\nAdiponectin is a hormone secreted by adipocytes that acts as an antidiabetic and anti-atherogenic adipokine. Two receptors for adiponectin have been identified: adiponectin receptor 1 (AdipoR1) and adiponectin receptor 2 (AdipoR2). They are seven-transmembrane domain receptors and mediate increased AMPK, MAPK and PPARA ligand activity in response to adiponectin. AdipoR1 is found in many tissues, being particularly abundant in skeletal muscle, whereas AdipoR2 is predominantly expressed in the liver (PMID: 24417942). AdipoR1 has a high affinity for globular adiponectin and a very low affinity for full-length adiponectin. AdipoR2 has an intermediate affinity for both forms. The human ADIPOR1 gene maps to chromosome 1q32.1, and encodes a 375-amino acid protein with a molecular weight of 43 kDa. This antibody was raised against 1-72aa of human AdipoR1.\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: Human\nCited Reactivity: human, mouse, pig\nHost \/ Isotype: Mouse \/ IgG1\nClass: Monoclonal\nType: Antibody\nImmunogen: CatNo: Ag18187 Product name: Recombinant human ADIPOR1 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 2-72 aa of BC010743 Sequence: SSHKGSVVAQGNGAPASNREADTVELAELGPLLEEKGKRVIANPPKAEEEQTCPVPQEEEEEVRVLTLPLQ Predict reactive species\nFull Name: adiponectin receptor 1\nCalculated Molecular Weight: 375 aa, 43 kDa\nObserved Molecular Weight: 43 kDa\nGenBank Accession Number: BC010743\nGene Symbol: Adiponectin receptor 1\nGene ID (NCBI): 51094\nRRID: AB_2881979\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Protein G purification\nUNIPROT ID: Q96A54\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46888002257065,"sku":"66619-1-Ig","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/proteintech-66619-1-ig","provider":"Iright","version":"1.0","type":"link"}