{"product_id":"proteintech-66851-2-ig","title":"Proteintech, 66851-2-Ig, SMO Monoclonal antibody","description":"Size: 20ul \/ 150ul\nThe SMO (66851-2-Ig) by Proteintech is a Monoclonal antibody targeting SMO in IF\/ICC, ELISA applications with reactivity to Human, Canine samples\n66851-2-Ig targets SMO in IF\/ICC, ELISA applications and shows reactivity with Human, Canine samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive IF\/ICC detected in: MDCK cells\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nImmunofluorescence (IF)\/ICC: IF\/ICC : 1:400-1:1600\n\u003cb\u003eBackground Information\u003c\/b\u003e\nSmoothened (SMO) is a G protein-coupled receptor that is a component of the hedgehog (Hh) signaling pathway and is conserved from flies to humans. The Hh pathway plays central roles in animal development and stem-cell function. Defects in Hh signalling lead to birth defects and cancer in humans. Expressed on the primary cilium, SMO interacts with the patched protein, a receptor for Hh proteins.\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: Human, Canine\nHost \/ Isotype: Mouse \/ IgG1\nClass: Monoclonal\nType: Antibody\nImmunogen: CatNo: Ag25861 Product name: Recombinant human SMO protein Source: e coli. -derived, PET28a Tag: 6*His Domain: 28-233 aa of BC009989 Sequence: RGAASSGNATGPGPRSAGGSARRSAAVTGPPPPLSHCGRAAPCEPLRYNVCLGSVLPYGATSTLLAGDSDSQEEAHGKLVLWSGLRNAPRCWAVIQPLLCAVYMPKCENDRVELPSRTLCQATRGPCAIVERERGWPDFLRCTPDRFPEGCTNEVQNIKFNSSGQCEVPLVRTDNPKSWYEDVEGCGIQCQNPLFTEAEHQDMHSY Predict reactive species\nFull Name: smoothened homolog (Drosophila)\nCalculated Molecular Weight: 787 aa, 86 kDa\nGenBank Accession Number: BC009989\nGene Symbol: SMO\nGene ID (NCBI): 6608\nRRID: AB_3085033\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Protein G purification\nUNIPROT ID: Q99835\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46888325284009,"sku":"66851-2-Ig","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/es\/products\/proteintech-66851-2-ig","provider":"Iright","version":"1.0","type":"link"}